On-line dialysis-SPE-CE of acidic drugs in biological samples.

J.R. Veraart; M.C.E. Groot; C. Gooijer; H. Lingeman; N.H. Velthorst; U.A.T. Brinkman

doi:10.1039/a807636g

On-line dialysis-SPE-CE of acidic drugs in biological samples.

J.R. Veraart, M.C.E. Groot, C. Gooijer, H. Lingeman, N.H. Velthorst, U.A.T. Brinkman

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

A fully automated method is presented for the determination of acidic drugs in urine and serum using on-line dialysis-solid-phase extraction (SPE)-capillary electrophoresis (CE) with UV detection. With non-steroidal anti-inflammatory drugs (NSAIDs) as test compounds, detection limits in the biological samples were 0.05-1.0 μg ml

Original language	English
Pages (from-to)	115-118
Journal	Analyst
Volume	124
DOIs	https://doi.org/10.1039/a807636g
Publication status	Published - 1999

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title = "On-line dialysis-SPE-CE of acidic drugs in biological samples.",

abstract = "A fully automated method is presented for the determination of acidic drugs in urine and serum using on-line dialysis-solid-phase extraction (SPE)-capillary electrophoresis (CE) with UV detection. With non-steroidal anti-inflammatory drugs (NSAIDs) as test compounds, detection limits in the biological samples were 0.05-1.0 μg ml",

author = "J.R. Veraart and M.C.E. Groot and C. Gooijer and H. Lingeman and N.H. Velthorst and U.A.T. Brinkman",

year = "1999",

doi = "10.1039/a807636g",

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journal = "Analyst",

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T1 - On-line dialysis-SPE-CE of acidic drugs in biological samples.

AU - Veraart, J.R.

AU - Groot, M.C.E.

AU - Gooijer, C.

AU - Lingeman, H.

AU - Velthorst, N.H.

AU - Brinkman, U.A.T.

PY - 1999

Y1 - 1999

N2 - A fully automated method is presented for the determination of acidic drugs in urine and serum using on-line dialysis-solid-phase extraction (SPE)-capillary electrophoresis (CE) with UV detection. With non-steroidal anti-inflammatory drugs (NSAIDs) as test compounds, detection limits in the biological samples were 0.05-1.0 μg ml

AB - A fully automated method is presented for the determination of acidic drugs in urine and serum using on-line dialysis-solid-phase extraction (SPE)-capillary electrophoresis (CE) with UV detection. With non-steroidal anti-inflammatory drugs (NSAIDs) as test compounds, detection limits in the biological samples were 0.05-1.0 μg ml

U2 - 10.1039/a807636g

DO - 10.1039/a807636g

M3 - Article

SN - 0003-2654

VL - 124

SP - 115

EP - 118

JO - Analyst

JF - Analyst

ER -

On-line dialysis-SPE-CE of acidic drugs in biological samples.

Abstract

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