A new [3 + 3]- and [3 + 4]-annulation strategy involving azaoxyallyl cation and [1,m]-amphoteric compounds (m = 3,4) is presented. This concise method enables easy assembly of functionalized saturated N-heterocycles, comprised of six-and seven-membered rings and is of high significance in the context of drug discovery approaches. This reaction also represents a new trapping modality of the azaoxyallyl cation with amphoteric agents of different chain lengths that consist of a heteroatom nucleophilic site and a π-electrophilic site.
FingerprintDive into the research topics of 'One-Step Assembly of Functionalized Morpholinones and 1,4-Oxazepane-3-ones via [3 + 3]- And [3 + 4]-Annulation of Aza-Oxyallyl Cation and Amphoteric Compounds'. Together they form a unique fingerprint.
Bera, T. (Contributor), Singh, B. (Contributor), Hamlin, T. A. (Contributor), Sahoo, S. C. (Contributor) & Saha, J. (Contributor), Unknown Publisher, 1 Jan 2021