Ontwikkelingen in de capillaire elektroforese

This article highlights some developments in the field of capillary electrophoresis (CE). Although the utilisation of CE in clinical chemistry is limited, some applications are already used in practice. Sensitivity is an important research area and several strategies such as stacking and different detection principles are discussed. Miniaturisation of CE hardware to chip size is one of the most fascinating developments. These chips are used in combination with all kinds of detectors and separation systems, including biosensors. The Micellar Electrokinetic Chromatography technique combines chromatographic with electrophoretic principles and offers great flexibility. Chiral CE is used within e.g. pharmaceutical analysis, research on stereoselective metabolism and forensic analysis.