Abstract
A new metric is used to improve the contrast of birefringent structures in biological tissue using polarization-sensitive optical coherence tomography. This metric, optic axis uniformity (OAxU), is based on the optic axis of birefringence and quantifies the uniformity of the optic axis direction. OAxU provides surprisingly strong contrast for fibrous structures such as muscle and the retinal nerve fiber layer (RNFL). We used OAxU for automatic segmentation of the RNFL in human eyes. From the segmentation, en face images of RNFL thickness and RNFL birefringence were created. The measured birefringence values are consistent with earlier reports.
Original language | English |
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Pages (from-to) | 3893-3896 |
Number of pages | 4 |
Journal | Optics Letters |
Volume | 44 |
Issue number | 15 |
Early online date | 9 Jul 2019 |
DOIs | |
Publication status | Published - 1 Aug 2019 |
Funding
Heidelberg Engineering; LaserLab Europe; Stichting voor de Technische Wetenschappen (STW); Health-Holland.
Funders | Funder number |
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Health-Holland | |
Stichting voor de Technische Wetenschappen |