Optimal Vitamin D Status: A Critical Analysis on the Basis of Evidence-Based Medicine

R. Bouillon; N.M. van Schoor; E. Gielen; S. Boonen; C. Mathieu; D. Vanderschueren; P.T.A.M. Lips

doi:10.1210/jc.2013-1195

Optimal Vitamin D Status: A Critical Analysis on the Basis of Evidence-Based Medicine

R. Bouillon, N.M. van Schoor, E. Gielen, S. Boonen, C. Mathieu, D. Vanderschueren, P.T.A.M. Lips

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Context: Public health authorities around the world recommend widely variable supplementation strategies for adults, whereas several professional organizations, including The Endocrine Society, recommend higher supplementation. Methods: We analyzed published randomized controlled clinical trials to define the optimal intake or vitamin D status for bone and extra skeletal health. Conclusions: The extra skeletal effects of vitamin D are plausible as based on preclinical data and observational studies. However, a part from the beneficial effectsof800IU/dofvitaminD

Original language	English
Pages (from-to)	E1283-E1304
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	98
Issue number	8
DOIs	https://doi.org/10.1210/jc.2013-1195
Publication status	Published - 2013

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10.1210/jc.2013-1195

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abstract = "Context: Public health authorities around the world recommend widely variable supplementation strategies for adults, whereas several professional organizations, including The Endocrine Society, recommend higher supplementation. Methods: We analyzed published randomized controlled clinical trials to define the optimal intake or vitamin D status for bone and extra skeletal health. Conclusions: The extra skeletal effects of vitamin D are plausible as based on preclinical data and observational studies. However, a part from the beneficial effectsof800IU/dofvitaminD",

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AU - Gielen, E.

AU - Boonen, S.

AU - Mathieu, C.

AU - Vanderschueren, D.

AU - Lips, P.T.A.M.

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AB - Context: Public health authorities around the world recommend widely variable supplementation strategies for adults, whereas several professional organizations, including The Endocrine Society, recommend higher supplementation. Methods: We analyzed published randomized controlled clinical trials to define the optimal intake or vitamin D status for bone and extra skeletal health. Conclusions: The extra skeletal effects of vitamin D are plausible as based on preclinical data and observational studies. However, a part from the beneficial effectsof800IU/dofvitaminD

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ER -

Optimal Vitamin D Status: A Critical Analysis on the Basis of Evidence-Based Medicine

Abstract

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