Palladium-catalyzed cross-coupling of a wide range of substituted o-(pseudo)halobenzoates and hydrazines with isocyanide insertion followed by lactamization efficiently affords 4-aminophthalazin-1(2H)-ones that are difficult to obtain regioselectively by classical methods.
|Number of pages||4|
|Publication status||Published - 15 Nov 2011|
- Molecular Structure
- Phthalazines/chemical synthesis