Parallel scanning laser ophthalmoscope for retinal imaging

K.V. Vienola, Mathivanan Damodaran, Boy Braaf, Mattijs de Groot, Koenraad Vermeer, Johannes F. de Boer

Research output: Contribution to ConferencePosterOther research output

Abstract

Introduction
High-speed imaging of the retina is crucial for obtaining high quality images in the presence of eye motion. To improve the speed of traditional scanners, a high-speed ophthalmic device is presented using a digital micro-mirror device (DMD) for confocal imaging with multiple simultaneous spots.

Methods
An experimental ophthalmic imaging system was constructed based on an 850 nm LED and a DMD containing 1024 x 768 micro-mirrors. Single mirror elements are sparsely turned ON to create multiple spots over the whole field of view. The DMD is programmed to project series of shifted point pattern configurations, effectively scanning the spots over the sample surface. The backscattered light from the retina is tapped off via a beam-splitter and imaged onto a CMOS camera. A confocal image is constructed by applying an image mask of virtual pinholes to each recorded frame. A wide-field confocal image is then created by combining all frames in a single image.

Results
In the figure a dollar note was imaged with all mirrors ON (widefield) and with multiple spots configuration (every 100th mirror ON). In widefield mode light is detected from different planes above and below the focal plane. When using multiple spots and virtual pinholes, only light from the focal plane is detected. The image on the right shows clearly the microstructure of the bank note.

Conclusions
It is possible to create confocal images with the PSLO system. In theory the DMD can achieve higher frame rates than traditional scanner-based systems (> 2 kHz) by illuminating the sample with multiple spots.
Original languageEnglish
Pages64-64
Number of pages1
Publication statusPublished - 7 Mar 2014
EventVU University Medical Center 8th Science Exchange Day - VU University Medical Center , Amsterdam, Netherlands
Duration: 7 Mar 20147 Mar 2014

Conference

ConferenceVU University Medical Center 8th Science Exchange Day
Abbreviated titleVUmc SED 2014
CountryNetherlands
CityAmsterdam
Period7/03/147/03/14

Fingerprint

mirrors
scanning
lasers
retina
pinholes
scanners
beam splitters
configurations
illuminating
field of view
CMOS
light emitting diodes
masks
cameras
high speed
microstructure

Keywords

  • retinal imaging
  • ophthalmic imaging
  • digital micromirror device
  • retina

Cite this

Vienola, K. V., Damodaran, M., Braaf, B., de Groot, M., Vermeer, K., & de Boer, J. F. (2014). Parallel scanning laser ophthalmoscope for retinal imaging. 64-64. Poster session presented at VU University Medical Center 8th Science Exchange Day, Amsterdam, Netherlands.
Vienola, K.V. ; Damodaran, Mathivanan ; Braaf, Boy ; de Groot, Mattijs ; Vermeer, Koenraad ; de Boer, Johannes F. / Parallel scanning laser ophthalmoscope for retinal imaging. Poster session presented at VU University Medical Center 8th Science Exchange Day, Amsterdam, Netherlands.1 p.
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keywords = "retinal imaging, ophthalmic imaging, digital micromirror device, retina",
author = "K.V. Vienola and Mathivanan Damodaran and Boy Braaf and {de Groot}, Mattijs and Koenraad Vermeer and {de Boer}, {Johannes F.}",
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Vienola, KV, Damodaran, M, Braaf, B, de Groot, M, Vermeer, K & de Boer, JF 2014, 'Parallel scanning laser ophthalmoscope for retinal imaging' VU University Medical Center 8th Science Exchange Day, Amsterdam, Netherlands, 7/03/14 - 7/03/14, pp. 64-64.

Parallel scanning laser ophthalmoscope for retinal imaging. / Vienola, K.V.; Damodaran, Mathivanan; Braaf, Boy; de Groot, Mattijs; Vermeer, Koenraad; de Boer, Johannes F.

2014. 64-64 Poster session presented at VU University Medical Center 8th Science Exchange Day, Amsterdam, Netherlands.

Research output: Contribution to ConferencePosterOther research output

TY - CONF

T1 - Parallel scanning laser ophthalmoscope for retinal imaging

AU - Vienola, K.V.

AU - Damodaran, Mathivanan

AU - Braaf, Boy

AU - de Groot, Mattijs

AU - Vermeer, Koenraad

AU - de Boer, Johannes F.

PY - 2014/3/7

Y1 - 2014/3/7

N2 - IntroductionHigh-speed imaging of the retina is crucial for obtaining high quality images in the presence of eye motion. To improve the speed of traditional scanners, a high-speed ophthalmic device is presented using a digital micro-mirror device (DMD) for confocal imaging with multiple simultaneous spots.MethodsAn experimental ophthalmic imaging system was constructed based on an 850 nm LED and a DMD containing 1024 x 768 micro-mirrors. Single mirror elements are sparsely turned ON to create multiple spots over the whole field of view. The DMD is programmed to project series of shifted point pattern configurations, effectively scanning the spots over the sample surface. The backscattered light from the retina is tapped off via a beam-splitter and imaged onto a CMOS camera. A confocal image is constructed by applying an image mask of virtual pinholes to each recorded frame. A wide-field confocal image is then created by combining all frames in a single image.ResultsIn the figure a dollar note was imaged with all mirrors ON (widefield) and with multiple spots configuration (every 100th mirror ON). In widefield mode light is detected from different planes above and below the focal plane. When using multiple spots and virtual pinholes, only light from the focal plane is detected. The image on the right shows clearly the microstructure of the bank note. ConclusionsIt is possible to create confocal images with the PSLO system. In theory the DMD can achieve higher frame rates than traditional scanner-based systems (> 2 kHz) by illuminating the sample with multiple spots.

AB - IntroductionHigh-speed imaging of the retina is crucial for obtaining high quality images in the presence of eye motion. To improve the speed of traditional scanners, a high-speed ophthalmic device is presented using a digital micro-mirror device (DMD) for confocal imaging with multiple simultaneous spots.MethodsAn experimental ophthalmic imaging system was constructed based on an 850 nm LED and a DMD containing 1024 x 768 micro-mirrors. Single mirror elements are sparsely turned ON to create multiple spots over the whole field of view. The DMD is programmed to project series of shifted point pattern configurations, effectively scanning the spots over the sample surface. The backscattered light from the retina is tapped off via a beam-splitter and imaged onto a CMOS camera. A confocal image is constructed by applying an image mask of virtual pinholes to each recorded frame. A wide-field confocal image is then created by combining all frames in a single image.ResultsIn the figure a dollar note was imaged with all mirrors ON (widefield) and with multiple spots configuration (every 100th mirror ON). In widefield mode light is detected from different planes above and below the focal plane. When using multiple spots and virtual pinholes, only light from the focal plane is detected. The image on the right shows clearly the microstructure of the bank note. ConclusionsIt is possible to create confocal images with the PSLO system. In theory the DMD can achieve higher frame rates than traditional scanner-based systems (> 2 kHz) by illuminating the sample with multiple spots.

KW - retinal imaging

KW - ophthalmic imaging

KW - digital micromirror device

KW - retina

M3 - Poster

SP - 64

EP - 64

ER -

Vienola KV, Damodaran M, Braaf B, de Groot M, Vermeer K, de Boer JF. Parallel scanning laser ophthalmoscope for retinal imaging. 2014. Poster session presented at VU University Medical Center 8th Science Exchange Day, Amsterdam, Netherlands.