Parkinson's disease, temporomandibular disorders and bruxism: A pilot study

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Background: Even though bruxism and Parkinson's disease (PD) share common characteristics, their relation is still not clear. Both bruxism and PD are movement disorders in addition, patients with bruxism as well as those with PD complain about musculoskeletal pain, including temporomandibular disorders (TMD) pain.

Objectives: Therefore, the aim of this pilot study was to gain more insight into the possible relation between bruxism and TMD on one hand and PD on the other.

Methods: In total, 801 persons gave their written informed consent and agreed to participate in the study filling in a questionnaire. Complete data were collected from 708 persons (368 with PD or Parkinsonism [PR] and 340 controls) and were included in the analysis. The questionnaire included the graded chronic pain scale, the DC/TMD oral behaviour checklist, the DC/TMD symptom questionnaire and the TMD pain screener. In addition, a question about self-reported tooth wear was included. The chi-square test and independent samples t test were used for the data analysis.

Results: Patients with PD/PR reported significantly more often bruxism during sleep and wakefulness than controls. Also, patients with PD/PR had more often possible TMD and reported a significantly higher mean pain intensity in the orofacial region than controls. There was no significant difference in complaints of jaw locking between the patient group and the control group. A tendency towards a significant association was found between PD/PR and tooth wear.

Conclusion: There is a relation between PD/PR and bruxism. Furthermore, a relation of PD/PR with TMD pain is suggested to be present.

Original languageEnglish
Pages (from-to)854-863
Number of pages10
JournalJournal of Oral Rehabilitation
Volume45
Issue number11
DOIs
Publication statusPublished - Nov 2018

Funding

The study protocol was reviewed from the medical ethics committee of the Free University Medical Centre (Vrij Universiteit Medisch Centrum-VUmc) and was considered not being covered by the Act Medical Scientific Research in Humans according to the Dutch legislation for medical research in humans (Wet medisch-wetenschapelijk onderzoek-WMO). This decision was made because of the cross-sectional study design and the use of the short questionnaire. As such, the study protocol was accepted by the medical ethics committee of the VUmc, who gave a non-WMO approval-statement (file no. 2015.461, approval date November 26th, 2015). An extra permission was given for an amendment (file no. A2016.459, approval date December 14th, 2016), in order to further expand our control group with participants recruited in public locations. Dr. Lobbezoo reports Grants and Other from Sunstar Suisse, grants from Somnomed, outside the submitted work. Dr. Aarab reports grants from SomnoMed, grants from Braebon Inc, grants from KNAW (The Royal Netherlands Academy of Arts and Sciences), grants from The Dutch Society of Gnathology and Prosthetic Dentistry, grants from American Equilibration Society, outside the

FundersFunder number
American Equilibration Society
Dutch Society of Gnathology and Prosthetic Dentistry
Sunstar Suisse
Koninklijke Nederlandse Akademie van Wetenschappen

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