TY - JOUR
T1 - Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
AU - Gusev, A.
AU - Lee, S.H.
AU - Trynka, G.
AU - Finucane, H.
AU - Vilhjálmsson, B.J.
AU - Xu, H.
AU - Zang, Z.
AU - Ripke, S.
AU - Bulik-Sullivan, B.K.
AU - Stahl, E.
AU - Kähler, A.K.
AU - Hultman, C. M.
AU - Purcell, S.M.
AU - McCarroll, S.A.
AU - Daly, M.
AU - Pasaniuc, B.
AU - Sullivan, P.F.
AU - Neale, B.M.
AU - Wray, N.R.
AU - Raychaudhuri, S.
AU - Price, A.L.
PY - 2014
Y1 - 2014
N2 - Regulatory and coding variants are known to be enriched with associations identified by genome-wide association studies (GWASs) of complex disease, but their contributions to trait heritability are currently unknown. We applied variance-component methods to imputed genotype data for 11 common diseases to partition the heritability explained by genotyped SNPs (h
AB - Regulatory and coding variants are known to be enriched with associations identified by genome-wide association studies (GWASs) of complex disease, but their contributions to trait heritability are currently unknown. We applied variance-component methods to imputed genotype data for 11 common diseases to partition the heritability explained by genotyped SNPs (h
UR - https://www.scopus.com/pages/publications/84922273141
UR - https://www.scopus.com/inward/citedby.url?scp=84922273141&partnerID=8YFLogxK
U2 - 10.1016/j.ajhg.2014.10.004
DO - 10.1016/j.ajhg.2014.10.004
M3 - Article
SN - 0002-9297
VL - 95
SP - 535
EP - 552
JO - American Journal of Human Genetics
JF - American Journal of Human Genetics
IS - 5
ER -
