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Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management

  • C.G.M. De Theije
  • , J. Wu
  • , S.L. Da Silva
  • , P.J. Kamphuis
  • , J. Garssen
  • , S.M. Korte
  • , A.D. Kraneveld

Research output: Chapter in Book / Report / Conference proceedingConference contributionAcademicpeer-review

Abstract

Autism spectrum disorders (ASDs) are pervasive neurodevelopmental disorders, characterized by impairments in social interaction and communication and the presence of limited, repetitive and stereotyped interests and behavior. Bowel symptoms are frequently reported in children with ASD and a potential role for gastrointestinal disturbances in ASD has been suggested. This review focuses on the importance of (allergic) gastrointestinal problems in ASD. We provide an overview of the possible gut-to-brain pathways and discuss opportunities for pharmaceutical and/or nutritional approaches for therapy. © 2011 Elsevier B.V. All rights reserved.
Original languageEnglish
Title of host publicationEuropean Journal of Pharmacology
DOIs
Publication statusPublished - Sept 2011
Externally publishedYes

Publication series

NameEuropean Journal of Pharmacology
ISSN (Print)0014-2999
ISSN (Electronic)1879-0712

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 2 - Zero Hunger
    SDG 2 Zero Hunger

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