Patients with spinal muscular atrophy use high percentages of trunk muscle capacity to perform seated tasks

Laura H C Peeters, Mariska M H P Janssen, Idsart Kingma, Jaap H van Dieën, Imelda J M de Groot

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

OBJECTIVE: To investigate trunk function during seated upper extremity tasks in patients with spinal muscular atrophy (SMA) type 2 and 3.

DESIGN: 17 persons with SMA and 15 healthy controls (HC) performed several tasks when sitting unsupported, such as reaching (and placing) forward and sideward. Joint torque and muscle activity were measured during maximum voluntary isometric contractions (MVIC). Three-dimensional kinematics and normalized muscle activity were analyzed when performing tasks.

RESULTS: Trunk joint torques were significantly decreased, approximately 45%, in patients with SMA compared to HC. Active range of trunk motion was also significantly decreased in all directions. When performing tasks, the average back muscle activity was 27% and 56% of MVIC for respectively HC and SMA, and for abdominal muscles respectively 10% and 44% of MVIC. Trunk range of motion did not differ when performing daily tasks.

CONCLUSION: The trunk of patients with SMA is weaker compared to HC, reflected by reduced trunk torques and decreased active range of motion. Additionally, patients with SMA use high percentages of their trunk muscle capacity to perform tasks. Clinicians should take this into account for intervention development, because using high percentages of the maximum muscle capacity results in fatigue and muscle overloading.

Original languageEnglish
Pages (from-to)1110-1117
JournalAmerican Journal of Physical Medicine and Rehabilitation
Volume98
Issue number12
Early online date2 Jul 2019
DOIs
Publication statusPublished - Dec 2019

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Spinal Muscular Atrophy
Isometric Contraction
Torque
Muscles
Articular Range of Motion
Joints
Spinal Muscular Atrophies of Childhood
Back Muscles
Abdominal Muscles
Muscle Fatigue
Biomechanical Phenomena
Upper Extremity

Cite this

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title = "Patients with spinal muscular atrophy use high percentages of trunk muscle capacity to perform seated tasks",
abstract = "OBJECTIVE: To investigate trunk function during seated upper extremity tasks in patients with spinal muscular atrophy (SMA) type 2 and 3.DESIGN: 17 persons with SMA and 15 healthy controls (HC) performed several tasks when sitting unsupported, such as reaching (and placing) forward and sideward. Joint torque and muscle activity were measured during maximum voluntary isometric contractions (MVIC). Three-dimensional kinematics and normalized muscle activity were analyzed when performing tasks.RESULTS: Trunk joint torques were significantly decreased, approximately 45{\%}, in patients with SMA compared to HC. Active range of trunk motion was also significantly decreased in all directions. When performing tasks, the average back muscle activity was 27{\%} and 56{\%} of MVIC for respectively HC and SMA, and for abdominal muscles respectively 10{\%} and 44{\%} of MVIC. Trunk range of motion did not differ when performing daily tasks.CONCLUSION: The trunk of patients with SMA is weaker compared to HC, reflected by reduced trunk torques and decreased active range of motion. Additionally, patients with SMA use high percentages of their trunk muscle capacity to perform tasks. Clinicians should take this into account for intervention development, because using high percentages of the maximum muscle capacity results in fatigue and muscle overloading.",
author = "Peeters, {Laura H C} and Janssen, {Mariska M H P} and Idsart Kingma and {van Die{\"e}n}, {Jaap H} and {de Groot}, {Imelda J M}",
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Patients with spinal muscular atrophy use high percentages of trunk muscle capacity to perform seated tasks. / Peeters, Laura H C; Janssen, Mariska M H P; Kingma, Idsart; van Dieën, Jaap H; de Groot, Imelda J M.

In: American Journal of Physical Medicine and Rehabilitation, Vol. 98, No. 12, 12.2019, p. 1110-1117.

Research output: Contribution to JournalArticleAcademicpeer-review

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T1 - Patients with spinal muscular atrophy use high percentages of trunk muscle capacity to perform seated tasks

AU - Peeters, Laura H C

AU - Janssen, Mariska M H P

AU - Kingma, Idsart

AU - van Dieën, Jaap H

AU - de Groot, Imelda J M

PY - 2019/12

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N2 - OBJECTIVE: To investigate trunk function during seated upper extremity tasks in patients with spinal muscular atrophy (SMA) type 2 and 3.DESIGN: 17 persons with SMA and 15 healthy controls (HC) performed several tasks when sitting unsupported, such as reaching (and placing) forward and sideward. Joint torque and muscle activity were measured during maximum voluntary isometric contractions (MVIC). Three-dimensional kinematics and normalized muscle activity were analyzed when performing tasks.RESULTS: Trunk joint torques were significantly decreased, approximately 45%, in patients with SMA compared to HC. Active range of trunk motion was also significantly decreased in all directions. When performing tasks, the average back muscle activity was 27% and 56% of MVIC for respectively HC and SMA, and for abdominal muscles respectively 10% and 44% of MVIC. Trunk range of motion did not differ when performing daily tasks.CONCLUSION: The trunk of patients with SMA is weaker compared to HC, reflected by reduced trunk torques and decreased active range of motion. Additionally, patients with SMA use high percentages of their trunk muscle capacity to perform tasks. Clinicians should take this into account for intervention development, because using high percentages of the maximum muscle capacity results in fatigue and muscle overloading.

AB - OBJECTIVE: To investigate trunk function during seated upper extremity tasks in patients with spinal muscular atrophy (SMA) type 2 and 3.DESIGN: 17 persons with SMA and 15 healthy controls (HC) performed several tasks when sitting unsupported, such as reaching (and placing) forward and sideward. Joint torque and muscle activity were measured during maximum voluntary isometric contractions (MVIC). Three-dimensional kinematics and normalized muscle activity were analyzed when performing tasks.RESULTS: Trunk joint torques were significantly decreased, approximately 45%, in patients with SMA compared to HC. Active range of trunk motion was also significantly decreased in all directions. When performing tasks, the average back muscle activity was 27% and 56% of MVIC for respectively HC and SMA, and for abdominal muscles respectively 10% and 44% of MVIC. Trunk range of motion did not differ when performing daily tasks.CONCLUSION: The trunk of patients with SMA is weaker compared to HC, reflected by reduced trunk torques and decreased active range of motion. Additionally, patients with SMA use high percentages of their trunk muscle capacity to perform tasks. Clinicians should take this into account for intervention development, because using high percentages of the maximum muscle capacity results in fatigue and muscle overloading.

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