Periodontal infection in cancer patients treated with high-dose chemotherapy

J.E. Raber-Durlacher; J.B. Epstein; J. Raber; J.T. van Dissel; A.J. van Winkelhoff; H.F. Guiot; U. van der Velden

doi:10.1007/s00520-002-0346-3

Periodontal infection in cancer patients treated with high-dose chemotherapy

J.E. Raber-Durlacher, J.B. Epstein, J. Raber, J.T. van Dissel, A.J. van Winkelhoff, H.F. Guiot, U. van der Velden

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

The infected and inflamed periodontium can act as a focus for systemic infection in neutropenic cancer patients. The incidence of these oral infections is unknown, but probably underestimated. Periodontal infections can easily be overlooked, primarily because symptoms of gingival inflammation may be minimal and the infection may be located in deeper parts of the periodontium. Assessment of a patient's periodontal condition before the onset of profound neutropenia is critical to the diagnosis and the management of these potentially life-threatening infections. This review article is aimed at informing supportive care providers of recent insights into the pathogenesis of periodontal diseases and the role of subgingival microorganisms, with the emphasis on these infections in cancer patients treated with high-dose chemotherapy. Furthermore, a multidisciplinary approach to the management of periodontal infections and the need for future research is discussed.

Original language	Undefined/Unknown
Pages (from-to)	466-473
Journal	Supportive Care in Cancer
Volume	10
Issue number	6
DOIs	https://doi.org/10.1007/s00520-002-0346-3
Publication status	Published - 2002

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Cite this

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title = "Periodontal infection in cancer patients treated with high-dose chemotherapy",

abstract = "The infected and inflamed periodontium can act as a focus for systemic infection in neutropenic cancer patients. The incidence of these oral infections is unknown, but probably underestimated. Periodontal infections can easily be overlooked, primarily because symptoms of gingival inflammation may be minimal and the infection may be located in deeper parts of the periodontium. Assessment of a patient's periodontal condition before the onset of profound neutropenia is critical to the diagnosis and the management of these potentially life-threatening infections. This review article is aimed at informing supportive care providers of recent insights into the pathogenesis of periodontal diseases and the role of subgingival microorganisms, with the emphasis on these infections in cancer patients treated with high-dose chemotherapy. Furthermore, a multidisciplinary approach to the management of periodontal infections and the need for future research is discussed.",

author = "J.E. Raber-Durlacher and J.B. Epstein and J. Raber and {van Dissel}, J.T. and {van Winkelhoff}, A.J. and H.F. Guiot and {van der Velden}, U.",

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doi = "10.1007/s00520-002-0346-3",

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T1 - Periodontal infection in cancer patients treated with high-dose chemotherapy

AU - Raber-Durlacher, J.E.

AU - Epstein, J.B.

AU - Raber, J.

AU - van Dissel, J.T.

AU - van Winkelhoff, A.J.

AU - Guiot, H.F.

AU - van der Velden, U.

PY - 2002

Y1 - 2002

N2 - The infected and inflamed periodontium can act as a focus for systemic infection in neutropenic cancer patients. The incidence of these oral infections is unknown, but probably underestimated. Periodontal infections can easily be overlooked, primarily because symptoms of gingival inflammation may be minimal and the infection may be located in deeper parts of the periodontium. Assessment of a patient's periodontal condition before the onset of profound neutropenia is critical to the diagnosis and the management of these potentially life-threatening infections. This review article is aimed at informing supportive care providers of recent insights into the pathogenesis of periodontal diseases and the role of subgingival microorganisms, with the emphasis on these infections in cancer patients treated with high-dose chemotherapy. Furthermore, a multidisciplinary approach to the management of periodontal infections and the need for future research is discussed.

AB - The infected and inflamed periodontium can act as a focus for systemic infection in neutropenic cancer patients. The incidence of these oral infections is unknown, but probably underestimated. Periodontal infections can easily be overlooked, primarily because symptoms of gingival inflammation may be minimal and the infection may be located in deeper parts of the periodontium. Assessment of a patient's periodontal condition before the onset of profound neutropenia is critical to the diagnosis and the management of these potentially life-threatening infections. This review article is aimed at informing supportive care providers of recent insights into the pathogenesis of periodontal diseases and the role of subgingival microorganisms, with the emphasis on these infections in cancer patients treated with high-dose chemotherapy. Furthermore, a multidisciplinary approach to the management of periodontal infections and the need for future research is discussed.

U2 - 10.1007/s00520-002-0346-3

DO - 10.1007/s00520-002-0346-3

M3 - Article

SN - 0941-4355

VL - 10

SP - 466

EP - 473

JO - Supportive Care in Cancer

JF - Supportive Care in Cancer

IS - 6

ER -