Aanhoudende vermoeidheid na een Q-koortsinfectie

Translated title of the contribution: Persistent fatigue following Q fever

Stephan P. Keijmel*, Gabriëlla Morroy, Corine E. Delsing, Gijs Bleijenberg, Chantal P. Bleeker-Rovers, Aura Timen

*Corresponding author for this work

    Research output: Contribution to JournalReview articleAcademicpeer-review


    In the Netherlands, more than 4000 patient cases of acute Q fever have been reported since 2007. Approximately 20% of these patients subsequently developed long-term fatigue. Such fatigue, as well as other physical symptoms and patient-perceived limitations in social functioning, have been compiled into what is known as the Q fever fatigue syndrome (QFS). The number of Dutch patients having QFS is expected to increase over the next years. The chance of a spontaneous recovery during the first six months following an acute Q fever infection is high. Allowing the fatigue to run its natural course is therefore justified. The diagnosis of QFS is based on history-taking, a physical examination and laboratory test results. The percentage of patients who recover spontaneously from QFS seems low. Data on outcome after treatment are not yet available. The recommendation is to refer patients with QFS to specialists who offer cognitive behavioural therapy for chronic fatigue syndrome or QFS. The objective of the recently published national guideline ‘Q fever fatigue syndrome (QFS)' is to achieve uniformity in its diagnosis and treatment.

    Translated title of the contributionPersistent fatigue following Q fever
    Original languageDutch
    Article numberA5258
    JournalNederlands Tijdschrift voor Geneeskunde
    Issue number48
    Publication statusPublished - 1 Dec 2012


    • Chronic Disease
    • Fatigue/diagnosis
    • Humans
    • Q Fever/complications
    • Watchful Waiting

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