Photohuperzine A-A new photoisomer of huperzine A: Structure elucidation, formation kinetics and activity assessment

L. de Azevedo Marques, M. Giera, F.J.J. de Kanter, W.M.A. Niessen, H. Lingeman, H. Irth

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

A new photoisomer of the promising " anti-Alzheimer" drug candidate (±) huperzine A is described. The new substance was formed via a photoisomerization reaction and was found to be 1-amino-13-ethylidene-11-methyl-6-aza-tetracyclo-[7.3.1.0
Original languageEnglish
Pages (from-to)190-194
Number of pages5
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume52
Issue number2
DOIs
Publication statusPublished - 2010

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