Photohuperzine A-A new photoisomer of huperzine A: Structure elucidation, formation kinetics and activity assessment

L. de Azevedo Marques; M. Giera; F.J.J. de Kanter; W.M.A. Niessen; H. Lingeman; H. Irth

doi:10.1016/j.jpba.2010.01.013

Photohuperzine A-A new photoisomer of huperzine A: Structure elucidation, formation kinetics and activity assessment

L. de Azevedo Marques, M. Giera, F.J.J. de Kanter, W.M.A. Niessen, H. Lingeman, H. Irth

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

A new photoisomer of the promising " anti-Alzheimer" drug candidate (±) huperzine A is described. The new substance was formed via a photoisomerization reaction and was found to be 1-amino-13-ethylidene-11-methyl-6-aza-tetracyclo-[7.3.1.0

Original language	English
Pages (from-to)	190-194
Number of pages	5
Journal	Journal of Pharmaceutical and Biomedical Analysis
Volume	52
Issue number	2
DOIs	https://doi.org/10.1016/j.jpba.2010.01.013
Publication status	Published - 2010

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10.1016/j.jpba.2010.01.013

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title = "Photohuperzine A-A new photoisomer of huperzine A: Structure elucidation, formation kinetics and activity assessment",

abstract = "A new photoisomer of the promising {"} anti-Alzheimer{"} drug candidate (±) huperzine A is described. The new substance was formed via a photoisomerization reaction and was found to be 1-amino-13-ethylidene-11-methyl-6-aza-tetracyclo-[7.3.1.0",

author = "{de Azevedo Marques}, L. and M. Giera and {de Kanter}, F.J.J. and W.M.A. Niessen and H. Lingeman and H. Irth",

year = "2010",

doi = "10.1016/j.jpba.2010.01.013",

language = "English",

volume = "52",

pages = "190--194",

journal = "Journal of Pharmaceutical and Biomedical Analysis",

issn = "0731-7085",

publisher = "Elsevier",

number = "2",

}

Photohuperzine A-A new photoisomer of huperzine A: Structure elucidation, formation kinetics and activity assessment. / de Azevedo Marques, L.; Giera, M.; de Kanter, F.J.J.; Niessen, W.M.A.; Lingeman, H.; Irth, H.

In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 52, No. 2, 2010, p. 190-194.

Research output: Contribution to Journal › Article › Academic › peer-review

TY - JOUR

T1 - Photohuperzine A-A new photoisomer of huperzine A: Structure elucidation, formation kinetics and activity assessment

AU - de Azevedo Marques, L.

AU - Giera, M.

AU - de Kanter, F.J.J.

AU - Niessen, W.M.A.

AU - Lingeman, H.

AU - Irth, H.

PY - 2010

Y1 - 2010

N2 - A new photoisomer of the promising " anti-Alzheimer" drug candidate (±) huperzine A is described. The new substance was formed via a photoisomerization reaction and was found to be 1-amino-13-ethylidene-11-methyl-6-aza-tetracyclo-[7.3.1.0

AB - A new photoisomer of the promising " anti-Alzheimer" drug candidate (±) huperzine A is described. The new substance was formed via a photoisomerization reaction and was found to be 1-amino-13-ethylidene-11-methyl-6-aza-tetracyclo-[7.3.1.0

U2 - 10.1016/j.jpba.2010.01.013

DO - 10.1016/j.jpba.2010.01.013

M3 - Article

VL - 52

SP - 190

EP - 194

JO - Journal of Pharmaceutical and Biomedical Analysis

JF - Journal of Pharmaceutical and Biomedical Analysis

SN - 0731-7085

IS - 2

ER -

Photohuperzine A-A new photoisomer of huperzine A: Structure elucidation, formation kinetics and activity assessment

Abstract

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