Physics of viral dynamics

Robijn F. Bruinsma; Gijs J.L. Wuite; Wouter H. Roos

doi:10.1038/s42254-020-00267-1

Physics of viral dynamics

Robijn F. Bruinsma, Gijs J.L. Wuite, Wouter H. Roos^*

^*Corresponding author for this work

Research output: Contribution to Journal › Review article › Academic › peer-review

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Abstract

Viral capsids are often regarded as inert structural units, but in actuality they display fascinating dynamics during different stages of their life cycle. With the advent of single-particle approaches and high-resolution techniques, it is now possible to scrutinize viral dynamics during and after their assembly and during the subsequent development pathway into infectious viruses. In this Review, the focus is on the dynamical properties of viruses, the different physical virology techniques that are being used to study them, and the physical concepts that have been developed to describe viral dynamics.

Original language	English
Pages (from-to)	76-91
Number of pages	16
Journal	Nature Reviews Physics
Volume	3
Issue number	2
Early online date	12 Jan 2021
DOIs	https://doi.org/10.1038/s42254-020-00267-1
Publication status	Published - Feb 2021

Funding

The authors thank C. Knobler for a critical reading of the manuscript, and C. Uetrecht and S. Maity for their input. W.H.R. is supported by a VIDI grant from the Nederlandse Oganizatie voor Wetenschappelijk Onderzoek. R.B. is supported by the NSF-DMR under CMMT grant 1836404.

Funders	Funder number
CMMT
NSF-DMR
National Science Foundation	1836404
Aard- en Levenswetenschappen, Nederlandse Organisatie voor Wetenschappelijk Onderzoek

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/s42254-020-00267-1

Physics of viral dynamicsFinal published version, 3.13 MBLicence: Article 25fa Dutch Copyright Act

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Physics of viral dynamics

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Funding

UN SDGs

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