Planar chromatography coupled with spectroscopic techniques.

G.W. Somsen, I.D. Wilson, W. Morden

Research output: Contribution to JournalArticleAcademicpeer-review


Recent progress in the combination of planar, or thin-layer chromatography (TLC) with a variety of modern spectroscopic techniques is reviewed. The utility of TLC for separation followed by mass spectrometry, with a variety of ionisation techniques, is illustrated with reference to a wide range of compound types including drugs, natural products, industrial chemicals, pesticides and dyes. Applications of the use of TLC in combination with Fourier transform infrared spectrometry (FTIR), near infrared spectroscopy and FTIR photoacoustic spectroscopy are discussed, together with the use of TLC with Raman spectroscopy. The use of conventional fluorescence spectroscopy and fluorescence line narrowing spectroscopy as an aid to compound identification is described. Lastly the coupling of TLC with other chromatographic techniques followed by spectroscopic evaluation is briefly considered. © 1995.
Original languageEnglish
Pages (from-to)613
JournalJournal of Chromatography A
Publication statusPublished - 1995


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