Polarization effects in optical coherence tomography of various biological tissues

JF de Boer; S. M. Srinivas; B.H. Park; TH Pham; ZP Chen; TE Milner; JS Nelson

doi:10.1109/2944.796347

Polarization effects in optical coherence tomography of various biological tissues

JF de Boer, S. M. Srinivas, B.H. Park, TH Pham, ZP Chen, TE Milner, JS Nelson

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Polarization sensitive optical coherence tomography (PS-OCT) was used to obtain spatially resolved ex vivo images of polarization changes in skeletal muscle, bone, skin and brain. Through coherent detection of two orthogonal polarization states of the signal formed by interference of light reflected from the biological sample and a mirror in the reference arm of a Michelson interferometer, the depth resolved change in polarization was measured. Inasmuch as any fibrous structure will influence the polarization of light, PS-OCT is a potentially powerful technique investigating tissue structural properties. In addition, the effects of single polarization state detection on OCT image formation is demonstrated.

Original language	English
Pages (from-to)	1200-1204
Journal	IEEE Journal of Selected Topics in Quantum Electronics
Volume	5
Issue number	4
DOIs	https://doi.org/10.1109/2944.796347
Publication status	Published - 1999

Keywords

biological tissues
biomedical imaging
birefringence
optical tomography
polarization

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@article{c4a8d0e2a11b44a081114d7dede23815,

title = "Polarization effects in optical coherence tomography of various biological tissues",

abstract = "Polarization sensitive optical coherence tomography (PS-OCT) was used to obtain spatially resolved ex vivo images of polarization changes in skeletal muscle, bone, skin and brain. Through coherent detection of two orthogonal polarization states of the signal formed by interference of light reflected from the biological sample and a mirror in the reference arm of a Michelson interferometer, the depth resolved change in polarization was measured. Inasmuch as any fibrous structure will influence the polarization of light, PS-OCT is a potentially powerful technique investigating tissue structural properties. In addition, the effects of single polarization state detection on OCT image formation is demonstrated.",

keywords = "biological tissues, biomedical imaging, birefringence, optical tomography, polarization",

author = "{de Boer}, JF and Srinivas, {S. M.} and B.H. Park and TH Pham and ZP Chen and TE Milner and JS Nelson",

year = "1999",

doi = "10.1109/2944.796347",

language = "English",

volume = "5",

pages = "1200--1204",

journal = "IEEE Journal of Selected Topics in Quantum Electronics",

issn = "1077-260X",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

number = "4",

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TY - JOUR

T1 - Polarization effects in optical coherence tomography of various biological tissues

AU - de Boer, JF

AU - Srinivas, S. M.

AU - Park, B.H.

AU - Pham, TH

AU - Chen, ZP

AU - Milner, TE

AU - Nelson, JS

PY - 1999

Y1 - 1999

N2 - Polarization sensitive optical coherence tomography (PS-OCT) was used to obtain spatially resolved ex vivo images of polarization changes in skeletal muscle, bone, skin and brain. Through coherent detection of two orthogonal polarization states of the signal formed by interference of light reflected from the biological sample and a mirror in the reference arm of a Michelson interferometer, the depth resolved change in polarization was measured. Inasmuch as any fibrous structure will influence the polarization of light, PS-OCT is a potentially powerful technique investigating tissue structural properties. In addition, the effects of single polarization state detection on OCT image formation is demonstrated.

AB - Polarization sensitive optical coherence tomography (PS-OCT) was used to obtain spatially resolved ex vivo images of polarization changes in skeletal muscle, bone, skin and brain. Through coherent detection of two orthogonal polarization states of the signal formed by interference of light reflected from the biological sample and a mirror in the reference arm of a Michelson interferometer, the depth resolved change in polarization was measured. Inasmuch as any fibrous structure will influence the polarization of light, PS-OCT is a potentially powerful technique investigating tissue structural properties. In addition, the effects of single polarization state detection on OCT image formation is demonstrated.

KW - biological tissues

KW - biomedical imaging

KW - birefringence

KW - optical tomography

KW - polarization

U2 - 10.1109/2944.796347

DO - 10.1109/2944.796347

M3 - Article

SN - 1077-260X

VL - 5

SP - 1200

EP - 1204

JO - IEEE Journal of Selected Topics in Quantum Electronics

JF - IEEE Journal of Selected Topics in Quantum Electronics

IS - 4

ER -

Polarization effects in optical coherence tomography of various biological tissues

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Keywords

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