Polymorphism in the glutathione conjugation activity of human erytrocytes towards ethylene dibromide and 1,2-epoxy-3-(p-nitrophenoxy)-propane.

J.P.H.T.M. Ploemen, L.W. Wormhoudt, B. van Ommen, J.N.M. Commandeur, N.P.E. Vermeulen, P.J. van Bladeren

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

In this study a polymorphism in the conjugating activity of human erythrocyte cytosol towards the dihaloethane, ethylene dibromide (EDB; 1,2-dibromoethane) was found. Two out of 12 human erythrocyte cytosols did not catalyze the formation of glutathione (GSH) conjugates of [1,2-
Original languageEnglish
Pages (from-to)469-476
JournalBiochimica et Biophysica Acta (BBA) - General Subjects
Volume1243
DOIs
Publication statusPublished - 1995

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