Practice, efficacy, and costs of thyroid nodule evaluation: a retrospective study in a Dutch university hospital.

L. Hooft, O.S. Hoekstra, M. Boers, M. van Tulder, P Van Diest, P.T.A.M. Lips

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Fine-needle aspiration (FNA) of thyroid nodules has markedly reduced the role of thyroid scintigraphy. This is often limited to nondiagnostic or follicular (tumor) FNA classifications. In this study, we evaluated the efficacy and cost of such a strategy in a university center. From 1992-1998, 995 aspirations were done in 667 patients with palpable nodules. FNA was classified as malignant, suspicious, follicular, benign or inadequate. The Gold standard was surgery or extended follow-up, including physical examination, FNA, and/or ultrasound (US) with a time interval of half a year. Cost analysis was limited to operated patients. The first FNA yielded inadequate results in 28%, decreasing to 6% after 4 aspirations (n = 42). The other final classifications were: 76%, benign; 14%, follicular; 2%, suspicious; 1%, malignant (n = 7). Scintigraphy (
Original languageEnglish
Pages (from-to)287-93
JournalThyroid
Volume14
Issue number4
Early online date1 Apr 2004
DOIs
Publication statusPublished - 2004

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