Prior expectation mediates neural adaptation to repeated sounds in the auditory cortex: An MEG study

Ana Todorovic, Freek van Ede, Eric Maris, Floris P. de Lange

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Repetition suppression, the phenomenon that the second presentation of a stimulus attenuates neural activity, is typically viewed as an automatic consequence of repeated stimulus presentation. However, a recent neuroimaging study has suggested that repetition suppression may be driven by top-down expectations. Here we examined whether and when repetition suppression can be modulated by top-down expectation. Participants listened to auditory stimuli in blocks where tone repetitions were either expected or unexpected, while we recorded ongoing neural activity using magneto encephalography. We found robust repetition suppression in the auditory cortex for repeated tones. Interestingly, this reduction was significantly larger for expected than unexpected repetitions, both in terms of evoked activity and gamma-band synchrony. These findings indicate a role of top-down expectation in generating repetition suppression and are in line with predictive coding models of perception, in which the difference between expected and actual input is propagated from lower to higher cortical areas.

Original languageEnglish
Pages (from-to)9118-9123
Number of pages6
JournalThe Journal of Neuroscience
Volume31
Issue number25
DOIs
Publication statusPublished - 22 Jun 2011
Externally publishedYes

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