Problem Management Plus (PM+) in the management of common mental disorders in a specialized mental healthcare facility in Pakistan; study protocol for a randomized controlled trial

Syed Usman Hamdani, Zainab Ahmed, Marit Sijbrandij, Huma Nazir, Aqsa Masood, Parveen Akhtar, Hania Amin, Richard A. Bryant, Katie Dawson, Mark Ommeren, Atif Rahman, Fareed Aslam Minhas

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Background: The World Health Organization (WHO) has developed Problem Management Plus (PM+), a 5-session, psychological intervention program delivered by trained non-specialist that addresses common mental disorders. The objectives of this study are to evaluate effectiveness and cost-effectiveness of PM+ in a specialized mental health care facility in Pakistan. Methods: A single blind individual randomized controlled trial (RCT) will be carried out in the outpatient department of a specialized mental healthcare facility in Rawalpindi, Pakistan. After informed consent, patients with high psychological distress (General Health Questionnaire-12 (score >2) and functional impairment (WHO Disability Assessment Schedule 2.0 score >16) will be randomised to PM+ plus treatment as usual (n = 96) or TAU only (n = 96). The primary outcome is the psychological distress, measured by levels of anxiety and depression on the Hospital Anxiety and Depression Scale and improvement in functioning as measured by WHODAS at 20 weeks after baseline. Secondary outcomes include improvement in symptoms of depression, post-traumatic stress disorder, levels of social support and cost effectiveness evaluation. Qualitative interviews will be conducted to evaluate the process of implementing PM+ including barriers and facilitators in implementation and possibility of integration of PM+ program in specialized mental health care facilities in Pakistan. Discussion: The results of this study will be helpful in evaluating the effectiveness of the approach of training non specialists, based in the specialized mental health care facilities in delivering evidence based psychological interventions in the low resource settings. Trial registration Australian New Zealand Clinical Trials Registry, ACTRN12616000381482. Registered Retrospectively on March 23, 2016

Original languageEnglish
Article number40
JournalInternational Journal of Mental Health Systems
Volume11
Issue number1
DOIs
Publication statusPublished - 8 Jun 2017

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Pakistan
Mental Disorders
Health Facilities
Randomized Controlled Trials
Psychology
Delivery of Health Care
Mental Health
Depression
Cost-Benefit Analysis
Anxiety
Single-Blind Method
Post-Traumatic Stress Disorders
Informed Consent
New Zealand
Social Support
Registries
Appointments and Schedules
Outpatients
Clinical Trials
Interviews

Keywords

  • Anxiety
  • Cognitive behavioural therapy
  • Common mental disorders
  • Depression
  • Integration
  • Low and middle income countries
  • Low resource settings
  • MhGAP
  • Non-specialist counsellors
  • Psychotherapy
  • Scale-up
  • Task-shifting
  • Trans-diagnostic

Cite this

Hamdani, Syed Usman ; Ahmed, Zainab ; Sijbrandij, Marit ; Nazir, Huma ; Masood, Aqsa ; Akhtar, Parveen ; Amin, Hania ; Bryant, Richard A. ; Dawson, Katie ; Ommeren, Mark ; Rahman, Atif ; Minhas, Fareed Aslam. / Problem Management Plus (PM+) in the management of common mental disorders in a specialized mental healthcare facility in Pakistan; study protocol for a randomized controlled trial. In: International Journal of Mental Health Systems. 2017 ; Vol. 11, No. 1.
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Problem Management Plus (PM+) in the management of common mental disorders in a specialized mental healthcare facility in Pakistan; study protocol for a randomized controlled trial. / Hamdani, Syed Usman; Ahmed, Zainab; Sijbrandij, Marit; Nazir, Huma; Masood, Aqsa; Akhtar, Parveen; Amin, Hania; Bryant, Richard A.; Dawson, Katie; Ommeren, Mark; Rahman, Atif; Minhas, Fareed Aslam.

In: International Journal of Mental Health Systems, Vol. 11, No. 1, 40, 08.06.2017.

Research output: Contribution to JournalArticleAcademicpeer-review

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AU - Hamdani, Syed Usman

AU - Ahmed, Zainab

AU - Sijbrandij, Marit

AU - Nazir, Huma

AU - Masood, Aqsa

AU - Akhtar, Parveen

AU - Amin, Hania

AU - Bryant, Richard A.

AU - Dawson, Katie

AU - Ommeren, Mark

AU - Rahman, Atif

AU - Minhas, Fareed Aslam

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