Proper receptor signalling in a mutant catfish gonadotropin-releasing hormone receptor lacking the highly conserved Asp(90) residue

M. Blomenrohr; R. Kuhne; E. Hund; R. Leurs; J. Bogerd; T.L. ter Laak

doi:10.1016/S0014-5793(01)02647-3

Proper receptor signalling in a mutant catfish gonadotropin-releasing hormone receptor lacking the highly conserved Asp(90) residue

M. Blomenrohr, R. Kuhne, E. Hund, R. Leurs, J. Bogerd, T.L. ter Laak

Medicinal chemistry

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

The negatively charged side chain of an Asp residue in transmembrane domain 2 is likely to play an important role in receptor signalling since it is highly conserved in the whole family of G protein-coupled receptors, except in mammalian gonadotropin-releasing hormone (GnRH) receptors. In this paper we show that the conserved Asp

Original language	English
Pages (from-to)	131-4
Journal	FEBS Letters
Volume	501
Issue number	2-3
DOIs	https://doi.org/10.1016/S0014-5793(01)02647-3
Publication status	Published - 2001

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S0014-5793(01)02647-3

Persistent URL (handle)

Copy link address

Cite this

@article{0153d6c429bf4ac9affb64ab29d4800e,

title = "Proper receptor signalling in a mutant catfish gonadotropin-releasing hormone receptor lacking the highly conserved Asp(90) residue",

abstract = "The negatively charged side chain of an Asp residue in transmembrane domain 2 is likely to play an important role in receptor signalling since it is highly conserved in the whole family of G protein-coupled receptors, except in mammalian gonadotropin-releasing hormone (GnRH) receptors. In this paper we show that the conserved Asp",

author = "M. Blomenrohr and R. Kuhne and E. Hund and R. Leurs and J. Bogerd and {ter Laak}, T.L.",

year = "2001",

doi = "10.1016/S0014-5793(01)02647-3",

language = "English",

volume = "501",

pages = "131--4",

journal = "FEBS Letters",

issn = "0014-5793",

publisher = "Elsevier",

number = "2-3",

}

TY - JOUR

T1 - Proper receptor signalling in a mutant catfish gonadotropin-releasing hormone receptor lacking the highly conserved Asp(90) residue

AU - Blomenrohr, M.

AU - Kuhne, R.

AU - Hund, E.

AU - Leurs, R.

AU - Bogerd, J.

AU - ter Laak, T.L.

PY - 2001

Y1 - 2001

N2 - The negatively charged side chain of an Asp residue in transmembrane domain 2 is likely to play an important role in receptor signalling since it is highly conserved in the whole family of G protein-coupled receptors, except in mammalian gonadotropin-releasing hormone (GnRH) receptors. In this paper we show that the conserved Asp

AB - The negatively charged side chain of an Asp residue in transmembrane domain 2 is likely to play an important role in receptor signalling since it is highly conserved in the whole family of G protein-coupled receptors, except in mammalian gonadotropin-releasing hormone (GnRH) receptors. In this paper we show that the conserved Asp

U2 - 10.1016/S0014-5793(01)02647-3

DO - 10.1016/S0014-5793(01)02647-3

M3 - Article

SN - 0014-5793

VL - 501

SP - 131

EP - 134

JO - FEBS Letters

JF - FEBS Letters

IS - 2-3

ER -

Proper receptor signalling in a mutant catfish gonadotropin-releasing hormone receptor lacking the highly conserved Asp(90) residue

Abstract

UN SDGs

Access to Document

Persistent URL (handle)

Fingerprint

Cite this