Proper receptor signalling in a mutant catfish gonadotropin-releasing hormone receptor lacking the highly conserved Asp(90) residue

M. Blomenrohr; R. Kuhne; E. Hund; R. Leurs; J. Bogerd; T.L. ter Laak

doi:10.1016/S0014-5793(01)02647-3

Proper receptor signalling in a mutant catfish gonadotropin-releasing hormone receptor lacking the highly conserved Asp(90) residue

M. Blomenrohr, R. Kuhne, E. Hund, R. Leurs, J. Bogerd, T.L. ter Laak

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

The negatively charged side chain of an Asp residue in transmembrane domain 2 is likely to play an important role in receptor signalling since it is highly conserved in the whole family of G protein-coupled receptors, except in mammalian gonadotropin-releasing hormone (GnRH) receptors. In this paper we show that the conserved Asp

Original language	English
Pages (from-to)	131-4
Journal	FEBS Letters
Volume	501
Issue number	2-3
DOIs	https://doi.org/10.1016/S0014-5793(01)02647-3
Publication status	Published - 2001

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10.1016/S0014-5793(01)02647-3

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title = "Proper receptor signalling in a mutant catfish gonadotropin-releasing hormone receptor lacking the highly conserved Asp(90) residue",

abstract = "The negatively charged side chain of an Asp residue in transmembrane domain 2 is likely to play an important role in receptor signalling since it is highly conserved in the whole family of G protein-coupled receptors, except in mammalian gonadotropin-releasing hormone (GnRH) receptors. In this paper we show that the conserved Asp",

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AU - Blomenrohr, M.

AU - Kuhne, R.

AU - Hund, E.

AU - Leurs, R.

AU - Bogerd, J.

AU - ter Laak, T.L.

PY - 2001

Y1 - 2001

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JO - FEBS Letters

JF - FEBS Letters

IS - 2-3

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Proper receptor signalling in a mutant catfish gonadotropin-releasing hormone receptor lacking the highly conserved Asp(90) residue

Abstract

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