Psychiatric and physical comorbidities and pain in patients with multiple sclerosis

Rogier Scherder, Neeltje Kant, Evelien T. Wolf, Bas Pijnenburg, Erik J.A. Scherder

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Background: It has been observed that patients with multiple sclerosis (MS), who have psychiatric and physical comorbidities such as depression and COPD, have an increased risk of experiencing more pain. In this study, we have distinguished between pain intensity and pain affect, as the latter, particularly, requires treatment. Furthermore, while pain and comorbidities have been assessed using questionnaires, this is possibly a less reliable method for those who are cognitively vulnerable. Objective: The aim of this study was to determine whether psychiatric and physical comorbidities can predict pain intensity and pain affect in MS patients, susceptible to cognitive impairment. Methods: Ninety-four patients with MS and 80 control participants participated in this cross-sectional study. Besides depression and anxiety, 47 additional comorbidities were extracted from patients’ medical records. Depression and anxiety were assessed using the Beck Depression Inventory and the Symptom Check List-90. Pain was assessed using the Number of Words Chosen Affective, Coloured Analog Scale, and the Faces Pain Scale. Cognitive functions, for example, memory and executive functions, were assessed using several neuropsychological tests. Results: The main findings indicate that psychiatric comorbidities (depression and anxiety) predict both pain intensity and pain affect and that total physical comorbidity predicts only pain affect in MS patients, susceptible to cognitive impairment. Conclusion: Both psychiatric and physical comorbidities predict pain affect. All three clinical outcomes enhance MS patients’ suffering.

LanguageEnglish
Pages325-334
Number of pages10
JournalJournal of Pain Research
Volume11
DOIs
Publication statusPublished - 13 Feb 2018

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Multiple Sclerosis
Psychiatry
Comorbidity
Pain
Depression
Anxiety
Facial Pain
Neuropsychological Tests
Executive Function
Psychological Stress
Chronic Obstructive Pulmonary Disease
Cognition
Medical Records
Cross-Sectional Studies
Equipment and Supplies

Keywords

  • Cognition
  • Comorbidities
  • Mood
  • Multiple sclerosis
  • Pain

Cite this

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title = "Psychiatric and physical comorbidities and pain in patients with multiple sclerosis",
abstract = "Background: It has been observed that patients with multiple sclerosis (MS), who have psychiatric and physical comorbidities such as depression and COPD, have an increased risk of experiencing more pain. In this study, we have distinguished between pain intensity and pain affect, as the latter, particularly, requires treatment. Furthermore, while pain and comorbidities have been assessed using questionnaires, this is possibly a less reliable method for those who are cognitively vulnerable. Objective: The aim of this study was to determine whether psychiatric and physical comorbidities can predict pain intensity and pain affect in MS patients, susceptible to cognitive impairment. Methods: Ninety-four patients with MS and 80 control participants participated in this cross-sectional study. Besides depression and anxiety, 47 additional comorbidities were extracted from patients’ medical records. Depression and anxiety were assessed using the Beck Depression Inventory and the Symptom Check List-90. Pain was assessed using the Number of Words Chosen Affective, Coloured Analog Scale, and the Faces Pain Scale. Cognitive functions, for example, memory and executive functions, were assessed using several neuropsychological tests. Results: The main findings indicate that psychiatric comorbidities (depression and anxiety) predict both pain intensity and pain affect and that total physical comorbidity predicts only pain affect in MS patients, susceptible to cognitive impairment. Conclusion: Both psychiatric and physical comorbidities predict pain affect. All three clinical outcomes enhance MS patients’ suffering.",
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Psychiatric and physical comorbidities and pain in patients with multiple sclerosis. / Scherder, Rogier; Kant, Neeltje; Wolf, Evelien T.; Pijnenburg, Bas; Scherder, Erik J.A.

In: Journal of Pain Research, Vol. 11, 13.02.2018, p. 325-334.

Research output: Contribution to JournalArticleAcademicpeer-review

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