TY - GEN
T1 - Psychopathic Genes
T2 - 8th International Conference on Computational Methods in Systems and Software, CoMeSySo 2024
AU - Augustinus, Femke
AU - Hendrikse, Sophie C.F.
AU - Treur, Jan
N1 - Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2026.
PY - 2026
Y1 - 2026
N2 - This paper investigates the role of epigenetics in the dynamics of psychopathy by designing and simulating a fifth-order multi-level adaptive network model. Understanding any disorder requires a comprehensive exploration of multiple dimensions. Therefore, this research proposes a computational model that takes into account (epi)genetic, neural, cognitive, and behavioural causal influences that generate psychopathic behaviour. It illustrates the impact of epigenetic influences on the genes MAO-A, 5-HTT, and OXTR and their consequences for other internal processes with regard to psychopathy. This paper includes a review of related literature in this research domain and the design and specifics of the adaptive network model addressing psychopathic behaviour. The model is evaluated by two simulations that show the difference in behaviour between individuals that at some point in their life develop psychopathy due to environmental circumstances and those not developing it. In addition, an extension of the model demonstrates the impact of cognitive behavioural therapy on an individual with psychopathy.
AB - This paper investigates the role of epigenetics in the dynamics of psychopathy by designing and simulating a fifth-order multi-level adaptive network model. Understanding any disorder requires a comprehensive exploration of multiple dimensions. Therefore, this research proposes a computational model that takes into account (epi)genetic, neural, cognitive, and behavioural causal influences that generate psychopathic behaviour. It illustrates the impact of epigenetic influences on the genes MAO-A, 5-HTT, and OXTR and their consequences for other internal processes with regard to psychopathy. This paper includes a review of related literature in this research domain and the design and specifics of the adaptive network model addressing psychopathic behaviour. The model is evaluated by two simulations that show the difference in behaviour between individuals that at some point in their life develop psychopathy due to environmental circumstances and those not developing it. In addition, an extension of the model demonstrates the impact of cognitive behavioural therapy on an individual with psychopathy.
KW - Adaptive Dynamic Modelling
KW - Epigenetics
KW - Multi-level
KW - Psychopathy
UR - https://www.scopus.com/pages/publications/105012355916
UR - https://www.scopus.com/inward/citedby.url?scp=105012355916&partnerID=8YFLogxK
U2 - 10.1007/978-3-031-94770-4_38
DO - 10.1007/978-3-031-94770-4_38
M3 - Conference contribution
AN - SCOPUS:105012355916
SN - 9783031947698
VL - 4
T3 - Lecture Notes in Networks and Systems
SP - 477
EP - 498
BT - System Design in Software Engineering
A2 - Silhavy, Radek
A2 - Silhavy, Petr
PB - Springer Nature Switzerland AG
Y2 - 12 October 2024 through 14 October 2024
ER -