Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses

L.A. van Tuijl; A.C. Voogd; A. de Graeff; A.W. Hoogendoorn; A.V. Ranchor; K.-Y. Pan; M. Basten; F. Lamers; M.I. Geerlings; J.G. Abell; P. Awadalla; M.F. Bakker; A.T.F. Beekman; O. Bjerkeset; A. Boyd; Y. Cui; H. Galenkamp; B. Garssen; S. Hellingman; M. Huisman; A. Huss; M.R. Keats; A.A.L. Kok; A.I. Luik; N. Noisel; N.C. Onland-Moret; Y. Payette; B.W.J.H. Penninx; L. Portengen; I. Rissanen; A.M. Roest; J.G.M. Rosmalen; R. Ruiter; R.A. Schoevers; D.M. Soave; M. Spaan; A. Steptoe; K. Stronks; E.R. Sund; E. Sweeney; A. Teyhan; I. Vaartjes; K.D. van der Willik; F.E. van Leeuwen; R. van Petersen; W.M.M. Verschuren; F. Visseren; R. Vermeulen; J. Dekker

doi:10.1002/brb3.2340

Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses

L.A. van Tuijl, A.C. Voogd, A. de Graeff, A.W. Hoogendoorn, A.V. Ranchor, K.-Y. Pan, M. Basten, F. Lamers, M.I. Geerlings, J.G. Abell, P. Awadalla, M.F. Bakker, A.T.F. Beekman, O. Bjerkeset, A. Boyd, Y. Cui, H. Galenkamp, B. Garssen, S. Hellingman, M. HuismanA. Huss, M.R. Keats, A.A.L. Kok, A.I. Luik, N. Noisel, N.C. Onland-Moret, Y. Payette, B.W.J.H. Penninx, L. Portengen, I. Rissanen, A.M. Roest, J.G.M. Rosmalen, R. Ruiter, R.A. Schoevers, D.M. Soave, M. Spaan, A. Steptoe, K. Stronks, E.R. Sund, E. Sweeney, A. Teyhan, I. Vaartjes, K.D. van der Willik, F.E. van Leeuwen, R. van Petersen, W.M.M. Verschuren, F. Visseren, R. Vermeulen, J. Dekker

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

OBJECTIVES: Psychosocial factors have been hypothesized to increase the risk of cancer. This study aims (1) to test whether psychosocial factors (depression, anxiety, recent loss events, subjective social support, relationship status, general distress, and neuroticism) are associated with the incidence of any cancer (any, breast, lung, prostate, colorectal, smoking-related, and alcohol-related); (2) to test the interaction between psychosocial factors and factors related to cancer risk (smoking, alcohol use, weight, physical activity, sedentary behavior, sleep, age, sex, education, hormone replacement therapy, and menopausal status) with regard to the incidence of cancer; and (3) to test the mediating role of health behaviors (smoking, alcohol use, weight, physical activity, sedentary behavior, and sleep) in the relationship between psychosocial factors and the incidence of cancer.

METHODS: The psychosocial factors and cancer incidence (PSY-CA) consortium was established involving experts in the field of (psycho-)oncology, methodology, and epidemiology. Using data collected in 18 cohorts (N = 617,355), a preplanned two-stage individual participant data (IPD) meta-analysis is proposed. Standardized analyses will be conducted on harmonized datasets for each cohort (stage 1), and meta-analyses will be performed on the risk estimates (stage 2).

CONCLUSION: PSY-CA aims to elucidate the relationship between psychosocial factors and cancer risk by addressing several shortcomings of prior meta-analyses.

Original language	English
Article number	e2340
Pages (from-to)	1-13
Number of pages	13
Journal	Brain and Behavior
Volume	11
Issue number	10
Early online date	2 Sept 2021
DOIs	https://doi.org/10.1002/brb3.2340
Publication status	Published - Oct 2021

Bibliographical note

Keywords

Anxiety
Cohort Studies
Humans
Incidence
Male
Meta-Analysis as Topic
Neoplasms/epidemiology
Social Support

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/brb3.2340

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Longitudinal Aging Study Amsterdam
Huisman, M. (Creator), van Tilburg, T. (Creator), Broese Van Groenou, M. (Creator), Suanet, B. (Creator), Visser, M. (Creator), Kok, A. A. L. (Creator), Hoogendijk, E. O. (Creator), Deeg, D. (Creator), Schaap, L. (Creator), Beekman, A. F. T. (Creator) & van Schoor, N. M. (Creator), Amsterdam UMC, 1992
http://www.lasa-vu.nl
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van Tuijl, L. A., Voogd, A. C., de Graeff, A., Hoogendoorn, A. W., Ranchor, A. V., Pan, K.-Y., Basten, M., Lamers, F., Geerlings, M. I., Abell, J. G., Awadalla, P., Bakker, M. F., Beekman, A. T. F., Bjerkeset, O., Boyd, A., Cui, Y., Galenkamp, H., Garssen, B., Hellingman, S., ... Dekker, J. (2021). Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses. Brain and Behavior, 11(10), 1-13. Article e2340. https://doi.org/10.1002/brb3.2340

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title = "Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses",

abstract = "OBJECTIVES: Psychosocial factors have been hypothesized to increase the risk of cancer. This study aims (1) to test whether psychosocial factors (depression, anxiety, recent loss events, subjective social support, relationship status, general distress, and neuroticism) are associated with the incidence of any cancer (any, breast, lung, prostate, colorectal, smoking-related, and alcohol-related); (2) to test the interaction between psychosocial factors and factors related to cancer risk (smoking, alcohol use, weight, physical activity, sedentary behavior, sleep, age, sex, education, hormone replacement therapy, and menopausal status) with regard to the incidence of cancer; and (3) to test the mediating role of health behaviors (smoking, alcohol use, weight, physical activity, sedentary behavior, and sleep) in the relationship between psychosocial factors and the incidence of cancer.METHODS: The psychosocial factors and cancer incidence (PSY-CA) consortium was established involving experts in the field of (psycho-)oncology, methodology, and epidemiology. Using data collected in 18 cohorts (N = 617,355), a preplanned two-stage individual participant data (IPD) meta-analysis is proposed. Standardized analyses will be conducted on harmonized datasets for each cohort (stage 1), and meta-analyses will be performed on the risk estimates (stage 2).CONCLUSION: PSY-CA aims to elucidate the relationship between psychosocial factors and cancer risk by addressing several shortcomings of prior meta-analyses.",

keywords = "Anxiety, Cohort Studies, Humans, Incidence, Male, Meta-Analysis as Topic, Neoplasms/epidemiology, Social Support",

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van Tuijl, LA, Voogd, AC, de Graeff, A, Hoogendoorn, AW, Ranchor, AV, Pan, K-Y, Basten, M, Lamers, F, Geerlings, MI, Abell, JG, Awadalla, P, Bakker, MF, Beekman, ATF, Bjerkeset, O, Boyd, A, Cui, Y, Galenkamp, H, Garssen, B, Hellingman, S, Huisman, M, Huss, A, Keats, MR, Kok, AAL, Luik, AI, Noisel, N, Onland-Moret, NC, Payette, Y, Penninx, BWJH, Portengen, L, Rissanen, I, Roest, AM, Rosmalen, JGM, Ruiter, R, Schoevers, RA, Soave, DM, Spaan, M, Steptoe, A, Stronks, K, Sund, ER, Sweeney, E, Teyhan, A, Vaartjes, I, van der Willik, KD, van Leeuwen, FE, van Petersen, R, Verschuren, WMM, Visseren, F, Vermeulen, R & Dekker, J 2021, 'Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses', Brain and Behavior, vol. 11, no. 10, e2340, pp. 1-13. https://doi.org/10.1002/brb3.2340

TY - JOUR

T1 - Psychosocial factors and cancer incidence (PSY-CA)

T2 - Protocol for individual participant data meta-analyses

AU - van Tuijl, L.A.

AU - Voogd, A.C.

AU - de Graeff, A.

AU - Hoogendoorn, A.W.

AU - Ranchor, A.V.

AU - Pan, K.-Y.

AU - Basten, M.

AU - Lamers, F.

AU - Geerlings, M.I.

AU - Abell, J.G.

AU - Awadalla, P.

AU - Bakker, M.F.

AU - Beekman, A.T.F.

AU - Bjerkeset, O.

AU - Boyd, A.

AU - Cui, Y.

AU - Galenkamp, H.

AU - Garssen, B.

AU - Hellingman, S.

AU - Huisman, M.

AU - Huss, A.

AU - Keats, M.R.

AU - Kok, A.A.L.

AU - Luik, A.I.

AU - Noisel, N.

AU - Onland-Moret, N.C.

AU - Payette, Y.

AU - Penninx, B.W.J.H.

AU - Portengen, L.

AU - Rissanen, I.

AU - Roest, A.M.

AU - Rosmalen, J.G.M.

AU - Ruiter, R.

AU - Schoevers, R.A.

AU - Soave, D.M.

AU - Spaan, M.

AU - Steptoe, A.

AU - Stronks, K.

AU - Sund, E.R.

AU - Sweeney, E.

AU - Teyhan, A.

AU - Vaartjes, I.

AU - van der Willik, K.D.

AU - van Leeuwen, F.E.

AU - van Petersen, R.

AU - Verschuren, W.M.M.

AU - Visseren, F.

AU - Vermeulen, R.

AU - Dekker, J.

PY - 2021/10

Y1 - 2021/10

N2 - OBJECTIVES: Psychosocial factors have been hypothesized to increase the risk of cancer. This study aims (1) to test whether psychosocial factors (depression, anxiety, recent loss events, subjective social support, relationship status, general distress, and neuroticism) are associated with the incidence of any cancer (any, breast, lung, prostate, colorectal, smoking-related, and alcohol-related); (2) to test the interaction between psychosocial factors and factors related to cancer risk (smoking, alcohol use, weight, physical activity, sedentary behavior, sleep, age, sex, education, hormone replacement therapy, and menopausal status) with regard to the incidence of cancer; and (3) to test the mediating role of health behaviors (smoking, alcohol use, weight, physical activity, sedentary behavior, and sleep) in the relationship between psychosocial factors and the incidence of cancer.METHODS: The psychosocial factors and cancer incidence (PSY-CA) consortium was established involving experts in the field of (psycho-)oncology, methodology, and epidemiology. Using data collected in 18 cohorts (N = 617,355), a preplanned two-stage individual participant data (IPD) meta-analysis is proposed. Standardized analyses will be conducted on harmonized datasets for each cohort (stage 1), and meta-analyses will be performed on the risk estimates (stage 2).CONCLUSION: PSY-CA aims to elucidate the relationship between psychosocial factors and cancer risk by addressing several shortcomings of prior meta-analyses.

AB - OBJECTIVES: Psychosocial factors have been hypothesized to increase the risk of cancer. This study aims (1) to test whether psychosocial factors (depression, anxiety, recent loss events, subjective social support, relationship status, general distress, and neuroticism) are associated with the incidence of any cancer (any, breast, lung, prostate, colorectal, smoking-related, and alcohol-related); (2) to test the interaction between psychosocial factors and factors related to cancer risk (smoking, alcohol use, weight, physical activity, sedentary behavior, sleep, age, sex, education, hormone replacement therapy, and menopausal status) with regard to the incidence of cancer; and (3) to test the mediating role of health behaviors (smoking, alcohol use, weight, physical activity, sedentary behavior, and sleep) in the relationship between psychosocial factors and the incidence of cancer.METHODS: The psychosocial factors and cancer incidence (PSY-CA) consortium was established involving experts in the field of (psycho-)oncology, methodology, and epidemiology. Using data collected in 18 cohorts (N = 617,355), a preplanned two-stage individual participant data (IPD) meta-analysis is proposed. Standardized analyses will be conducted on harmonized datasets for each cohort (stage 1), and meta-analyses will be performed on the risk estimates (stage 2).CONCLUSION: PSY-CA aims to elucidate the relationship between psychosocial factors and cancer risk by addressing several shortcomings of prior meta-analyses.

KW - Anxiety

KW - Cohort Studies

KW - Humans

KW - Incidence

KW - Male

KW - Meta-Analysis as Topic

KW - Neoplasms/epidemiology

KW - Social Support

U2 - 10.1002/brb3.2340

DO - 10.1002/brb3.2340

M3 - Article

C2 - 34473425

SN - 2162-3279

VL - 11

SP - 1

EP - 13

JO - Brain and Behavior

JF - Brain and Behavior

IS - 10

M1 - e2340

ER -

Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

Persistent URL (handle)

Fingerprint

Datasets

Longitudinal Aging Study Amsterdam

Cite this