Quality of daily-life gait: Novel outcome for trials that focus on balance, mobility, and falls

Kimberley S. van Schooten*, Mirjam Pijnappels, Jaap H. van Dieën, Stephen R. Lord

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Technological advances in inertial sensors allow for monitoring of daily-life gait characteristics as a proxy for fall risk. The quality of daily-life gait could serve as a valuable outcome for intervention trials, but the uptake of these measures relies on their power to detect relevant changes in fall risk. We collected daily-life gait characteristics in 163 older people (aged 77.5 ± 7.5, 107♀) over two measurement weeks that were two weeks apart. We present variance estimates of daily-life gait characteristics that are sensitive to fall risk and estimate the number of participants required to obtain sufficient statistical power for repeated comparisons. The provided data allows for power analyses for studies using daily-life gait quality as outcome. Our results show that the number of participants required (i.e., 8 to 343 depending on the anticipated effect size and between-measurements correlation) is similar to that generally used in fall prevention trials. We propose that the quality of daily-life gait is a promising outcome for intervention studies that focus on improving balance and mobility and reducing falls.

Original languageEnglish
Article number4388
Pages (from-to)1-9
Number of pages9
JournalSensors (Switzerland)
Volume19
Issue number20
DOIs
Publication statusPublished - 11 Oct 2019

Funding

Funding: This work was supported by the Dutch Organization for Scientific Research [NWO TOP NIG grant 91209021] and the Human Frontier Science program [HFSP long-term fellowship number LT001080/2017].

FundersFunder number
Dutch Organization for Scientific Research
NWO TOP NIGTOP
Human Frontier Science Program
Human Frontier Science ProgramLT001080/2017
Nederlandse Organisatie voor Wetenschappelijk Onderzoek91209021

    Keywords

    • Accelerometry
    • Accidental falls
    • Activity monitoring
    • Aged
    • Intervention studies

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