TY - JOUR
T1 - Quality of life and cognitive function in patients with pituitary insufficiency
AU - Burman, P.
AU - Deijen, J.B.
PY - 1998
Y1 - 1998
N2 - This review is concerned with the psychosocial functioning and the quality of life in patients with pituitary insufficiency who are receiving conventional hormone replacement therapy. The possible negative effects of pituitary surgery, treatment with irradiation, and suboptimal replacement regimens with hormones other than growth hormone on mood, behaviour and cognitive functioning are discussed. The influence of growth hormone deficiency per se, and the outcome of growth hormone therapy in adult patients are addressed in detail. A possible mechanism for a direct effect of growth hormone on the brain is presented.
AB - This review is concerned with the psychosocial functioning and the quality of life in patients with pituitary insufficiency who are receiving conventional hormone replacement therapy. The possible negative effects of pituitary surgery, treatment with irradiation, and suboptimal replacement regimens with hormones other than growth hormone on mood, behaviour and cognitive functioning are discussed. The influence of growth hormone deficiency per se, and the outcome of growth hormone therapy in adult patients are addressed in detail. A possible mechanism for a direct effect of growth hormone on the brain is presented.
UR - https://www.scopus.com/pages/publications/0031841264
UR - https://www.scopus.com/inward/citedby.url?scp=0031841264&partnerID=8YFLogxK
U2 - 10.1159/000012276
DO - 10.1159/000012276
M3 - Article
SN - 0033-3190
VL - 67
SP - 154
EP - 167
JO - Psychotherapy and Psychosomatics
JF - Psychotherapy and Psychosomatics
IS - 3
ER -