Quality of life and health status of Indonesian women with breast cancer symptoms before the definitive diagnosis: A comparison with Indonesian women in general

Hari Setyowibowo, Fredrick Dermawan Purba, Joke A.M. Hunfeld, Aulia Iskandarsyah, Sawitri S. Sadarjoen, Jan Passchier, Marit Sijbrandij

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Objectives Breast cancer (BC) is prevalent in low and middle-income countries (LMICs) where the majority of cases are diagnosed in late stages. The aims of this study were: (1) to assess quality of life (QOL) and health status of Indonesian women with BC symptoms before definitive diagnosis; (2) to compare QOL and health status between women with BC symptoms before definitive diagnosis and Indonesian women in general; (3) to evaluate the association between demographic variables (age, residence, social economic status and education level) and QOL within the Indonesian women with BC symptoms before definitive diagnosis. Methods We used WHOQOL-BREF to measure QOL and EQ-5D-5L for health status. Multivariate analysis of covariance (MANCOVA) was used to compare QOL and health status between women with BC symptoms and women from the general Indonesian population in order to control for confounders. Regression analyses were used for testing the association between the demographic variables, QOL, and health status. Results In comparison with the data from the women from the general population (n = 471), the women with BC symptoms (n = 132) reported lower QOL, especially in physical and psychological domains. They also reported more problems in all dimensions of health status. Higher education and monthly income were positively associated with QOL and health status among the women with BC symptoms. Conclusion Before receiving a definitive diagnosis, women who visit hospitals with symptoms of BC, report a lower QOL and health status than women in general. Our results suggest that healthcare providers should provide targeted strategies for women with BC symptoms to improve their QOL.

Original languageEnglish
Article numbere0200966
Pages (from-to)1-11
Number of pages11
JournalPLoS ONE
Volume13
Issue number7
DOIs
Publication statusPublished - 19 Jul 2018

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health status
quality of life
breast neoplasms
Health Status
signs and symptoms (animals and humans)
Quality of Life
Health
Breast Neoplasms
Education
income
demographic statistics
Demography
higher education
educational status
socioeconomic status
Health Personnel
health services
Population
Economics
multivariate analysis

Cite this

@article{3077b51ade2a440385f84ee95f1369e1,
title = "Quality of life and health status of Indonesian women with breast cancer symptoms before the definitive diagnosis: A comparison with Indonesian women in general",
abstract = "Objectives Breast cancer (BC) is prevalent in low and middle-income countries (LMICs) where the majority of cases are diagnosed in late stages. The aims of this study were: (1) to assess quality of life (QOL) and health status of Indonesian women with BC symptoms before definitive diagnosis; (2) to compare QOL and health status between women with BC symptoms before definitive diagnosis and Indonesian women in general; (3) to evaluate the association between demographic variables (age, residence, social economic status and education level) and QOL within the Indonesian women with BC symptoms before definitive diagnosis. Methods We used WHOQOL-BREF to measure QOL and EQ-5D-5L for health status. Multivariate analysis of covariance (MANCOVA) was used to compare QOL and health status between women with BC symptoms and women from the general Indonesian population in order to control for confounders. Regression analyses were used for testing the association between the demographic variables, QOL, and health status. Results In comparison with the data from the women from the general population (n = 471), the women with BC symptoms (n = 132) reported lower QOL, especially in physical and psychological domains. They also reported more problems in all dimensions of health status. Higher education and monthly income were positively associated with QOL and health status among the women with BC symptoms. Conclusion Before receiving a definitive diagnosis, women who visit hospitals with symptoms of BC, report a lower QOL and health status than women in general. Our results suggest that healthcare providers should provide targeted strategies for women with BC symptoms to improve their QOL.",
author = "Hari Setyowibowo and Purba, {Fredrick Dermawan} and Hunfeld, {Joke A.M.} and Aulia Iskandarsyah and Sadarjoen, {Sawitri S.} and Jan Passchier and Marit Sijbrandij",
year = "2018",
month = "7",
day = "19",
doi = "10.1371/journal.pone.0200966",
language = "English",
volume = "13",
pages = "1--11",
journal = "PLoS ONE",
issn = "1932-6203",
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Quality of life and health status of Indonesian women with breast cancer symptoms before the definitive diagnosis : A comparison with Indonesian women in general. / Setyowibowo, Hari; Purba, Fredrick Dermawan; Hunfeld, Joke A.M.; Iskandarsyah, Aulia; Sadarjoen, Sawitri S.; Passchier, Jan; Sijbrandij, Marit.

In: PLoS ONE, Vol. 13, No. 7, e0200966, 19.07.2018, p. 1-11.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - Quality of life and health status of Indonesian women with breast cancer symptoms before the definitive diagnosis

T2 - A comparison with Indonesian women in general

AU - Setyowibowo, Hari

AU - Purba, Fredrick Dermawan

AU - Hunfeld, Joke A.M.

AU - Iskandarsyah, Aulia

AU - Sadarjoen, Sawitri S.

AU - Passchier, Jan

AU - Sijbrandij, Marit

PY - 2018/7/19

Y1 - 2018/7/19

N2 - Objectives Breast cancer (BC) is prevalent in low and middle-income countries (LMICs) where the majority of cases are diagnosed in late stages. The aims of this study were: (1) to assess quality of life (QOL) and health status of Indonesian women with BC symptoms before definitive diagnosis; (2) to compare QOL and health status between women with BC symptoms before definitive diagnosis and Indonesian women in general; (3) to evaluate the association between demographic variables (age, residence, social economic status and education level) and QOL within the Indonesian women with BC symptoms before definitive diagnosis. Methods We used WHOQOL-BREF to measure QOL and EQ-5D-5L for health status. Multivariate analysis of covariance (MANCOVA) was used to compare QOL and health status between women with BC symptoms and women from the general Indonesian population in order to control for confounders. Regression analyses were used for testing the association between the demographic variables, QOL, and health status. Results In comparison with the data from the women from the general population (n = 471), the women with BC symptoms (n = 132) reported lower QOL, especially in physical and psychological domains. They also reported more problems in all dimensions of health status. Higher education and monthly income were positively associated with QOL and health status among the women with BC symptoms. Conclusion Before receiving a definitive diagnosis, women who visit hospitals with symptoms of BC, report a lower QOL and health status than women in general. Our results suggest that healthcare providers should provide targeted strategies for women with BC symptoms to improve their QOL.

AB - Objectives Breast cancer (BC) is prevalent in low and middle-income countries (LMICs) where the majority of cases are diagnosed in late stages. The aims of this study were: (1) to assess quality of life (QOL) and health status of Indonesian women with BC symptoms before definitive diagnosis; (2) to compare QOL and health status between women with BC symptoms before definitive diagnosis and Indonesian women in general; (3) to evaluate the association between demographic variables (age, residence, social economic status and education level) and QOL within the Indonesian women with BC symptoms before definitive diagnosis. Methods We used WHOQOL-BREF to measure QOL and EQ-5D-5L for health status. Multivariate analysis of covariance (MANCOVA) was used to compare QOL and health status between women with BC symptoms and women from the general Indonesian population in order to control for confounders. Regression analyses were used for testing the association between the demographic variables, QOL, and health status. Results In comparison with the data from the women from the general population (n = 471), the women with BC symptoms (n = 132) reported lower QOL, especially in physical and psychological domains. They also reported more problems in all dimensions of health status. Higher education and monthly income were positively associated with QOL and health status among the women with BC symptoms. Conclusion Before receiving a definitive diagnosis, women who visit hospitals with symptoms of BC, report a lower QOL and health status than women in general. Our results suggest that healthcare providers should provide targeted strategies for women with BC symptoms to improve their QOL.

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