Quality of life in community-dwelling Dutch elderly measured by EQ-5D-3L

M.-J.J. Mangen; M. Bolkenbaas; S.M. Huijts; C.H. van Werkhoven; M.J.M. Bonten; G.A. de Wit

doi:10.1186/s12955-016-0577-5

Quality of life in community-dwelling Dutch elderly measured by EQ-5D-3L

M.-J.J. Mangen, M. Bolkenbaas, S.M. Huijts, C.H. van Werkhoven, M.J.M. Bonten, G.A. de Wit

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

© 2017 The Author(s).Background: We aimed to evaluate health status and associated factors in community-dwelling elderly in the Netherlands. Methods: Participants from a placebo-controlled double-blind randomized controlled trial conducted in the Netherlands were invited at the time of enrolment to participate in this study. Data were collected on comorbidities, socio-demographic background and health status, using EQ-5D-3L instrument. EQ-5D-3L summary index values (EQ-5D-indices) was derived using Dutch tariff. Regression analysis was conducted to identify factors associated with EQ-5D-indices and visual analogue scale (EQ-VAS). Results: 48,634 elderly (≥65 years) were included. The most frequently reported complaint was pain/discomfort (29.4%), but for the elder elderly (i.e. ≥85 years) it was mobility (52.9%). The proportion of persons reporting (multiple) problems increased with age from 31.5% for 65-69 years old subjects to 65.9% for elder elderly. The mean EQ-5D-indices and EQ-VAS decreased with age from 0.94 and 84, respectively in those 65 to 69 years old to 0.86 and 76, respectively, in ≥85 years old subjects. Increasing age, female gender, low education, geographic factors and comorbidities were associated with impaired health status. Conclusions: Within community-dwelling elderly large differences in health status exist. Impairment increases rapidly with age, but health status is also associated with socio-demographic variables and comorbidities. Trial registration: ClinicalTrials.gov, NCT00812084.

Original language	English
Article number	3
Journal	Health and Quality of Life Outcomes
Volume	15
Issue number	1
DOIs	https://doi.org/10.1186/s12955-016-0577-5
Publication status	Published - 6 Jan 2017
Externally published	Yes

Funding

Bolkenbaas reports receipt of presentation honorary from Pfizer. Bonten reports receipt of research funding from Pfizer, and service on the “Community-Acquired Pneumonia immunization Trial in Adults” (CAPiTA) European Expert Meeting. Huijts reports receipt of financial support for printing her PhD thesis from Pfizer. Mangen declares fees paid by GSK to the institution for participating in model building. Van Werkhoven reports service in a Pfizer Advisory Committee. De Wit reports receipt of unrestricted research grant from Pfizer. Bolkenbaas, Huijts, Mangen and van Werkhoven’s research funding is partially supported by grants provided to UMCU by Pfizer. Bolkenbaas, Bonten, Huijts, Mangen, van Werkhoven and de Wit are UMCU employees. No other disclosures were reported. The authors would like to thank all “Costs, Health status and Outcomes of community-acquired pneumonia (CAP)” (CHO-CAP) participants for their participation. The “Community-Acquired Pneumonia immunization Trial in Adults” (CAPiTA) team and the CHO-CAP-team from Julius Clinical B.V. in Zeist are acknowledged for their logistic support during the data collection. Bente S. Dikken, medical student at University Medical Center Utrecht, is acknowledged for some preliminary data cleaning. The CHO-CAP study is made possible by an unrestricted grant from Wyeth Pharmaceuticals, which was acquired by Pfizer Inc. in October 2009, to the University of Medical Centre of Utrecht. The CHO-CAP study is made possible by an unrestricted grant from Wyeth Pharmaceuticals, which was acquired by Pfizer Inc. in October 2009, to the University of Medical Centre of Utrecht.

Funders	Funder number
CAPiTA
UMCU
University of Medical Centre of Utrecht
Pfizer
Wyeth Pharmaceuticals

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title = "Quality of life in community-dwelling Dutch elderly measured by EQ-5D-3L",

abstract = "{\textcopyright} 2017 The Author(s).Background: We aimed to evaluate health status and associated factors in community-dwelling elderly in the Netherlands. Methods: Participants from a placebo-controlled double-blind randomized controlled trial conducted in the Netherlands were invited at the time of enrolment to participate in this study. Data were collected on comorbidities, socio-demographic background and health status, using EQ-5D-3L instrument. EQ-5D-3L summary index values (EQ-5D-indices) was derived using Dutch tariff. Regression analysis was conducted to identify factors associated with EQ-5D-indices and visual analogue scale (EQ-VAS). Results: 48,634 elderly (≥65 years) were included. The most frequently reported complaint was pain/discomfort (29.4%), but for the elder elderly (i.e. ≥85 years) it was mobility (52.9%). The proportion of persons reporting (multiple) problems increased with age from 31.5% for 65-69 years old subjects to 65.9% for elder elderly. The mean EQ-5D-indices and EQ-VAS decreased with age from 0.94 and 84, respectively in those 65 to 69 years old to 0.86 and 76, respectively, in ≥85 years old subjects. Increasing age, female gender, low education, geographic factors and comorbidities were associated with impaired health status. Conclusions: Within community-dwelling elderly large differences in health status exist. Impairment increases rapidly with age, but health status is also associated with socio-demographic variables and comorbidities. Trial registration: ClinicalTrials.gov, NCT00812084.",

author = "M.-J.J. Mangen and M. Bolkenbaas and S.M. Huijts and {van Werkhoven}, C.H. and M.J.M. Bonten and {de Wit}, G.A.",

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doi = "10.1186/s12955-016-0577-5",

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AU - Mangen, M.-J.J.

AU - Bolkenbaas, M.

AU - Huijts, S.M.

AU - van Werkhoven, C.H.

AU - Bonten, M.J.M.

AU - de Wit, G.A.

PY - 2017/1/6

Y1 - 2017/1/6

N2 - © 2017 The Author(s).Background: We aimed to evaluate health status and associated factors in community-dwelling elderly in the Netherlands. Methods: Participants from a placebo-controlled double-blind randomized controlled trial conducted in the Netherlands were invited at the time of enrolment to participate in this study. Data were collected on comorbidities, socio-demographic background and health status, using EQ-5D-3L instrument. EQ-5D-3L summary index values (EQ-5D-indices) was derived using Dutch tariff. Regression analysis was conducted to identify factors associated with EQ-5D-indices and visual analogue scale (EQ-VAS). Results: 48,634 elderly (≥65 years) were included. The most frequently reported complaint was pain/discomfort (29.4%), but for the elder elderly (i.e. ≥85 years) it was mobility (52.9%). The proportion of persons reporting (multiple) problems increased with age from 31.5% for 65-69 years old subjects to 65.9% for elder elderly. The mean EQ-5D-indices and EQ-VAS decreased with age from 0.94 and 84, respectively in those 65 to 69 years old to 0.86 and 76, respectively, in ≥85 years old subjects. Increasing age, female gender, low education, geographic factors and comorbidities were associated with impaired health status. Conclusions: Within community-dwelling elderly large differences in health status exist. Impairment increases rapidly with age, but health status is also associated with socio-demographic variables and comorbidities. Trial registration: ClinicalTrials.gov, NCT00812084.

AB - © 2017 The Author(s).Background: We aimed to evaluate health status and associated factors in community-dwelling elderly in the Netherlands. Methods: Participants from a placebo-controlled double-blind randomized controlled trial conducted in the Netherlands were invited at the time of enrolment to participate in this study. Data were collected on comorbidities, socio-demographic background and health status, using EQ-5D-3L instrument. EQ-5D-3L summary index values (EQ-5D-indices) was derived using Dutch tariff. Regression analysis was conducted to identify factors associated with EQ-5D-indices and visual analogue scale (EQ-VAS). Results: 48,634 elderly (≥65 years) were included. The most frequently reported complaint was pain/discomfort (29.4%), but for the elder elderly (i.e. ≥85 years) it was mobility (52.9%). The proportion of persons reporting (multiple) problems increased with age from 31.5% for 65-69 years old subjects to 65.9% for elder elderly. The mean EQ-5D-indices and EQ-VAS decreased with age from 0.94 and 84, respectively in those 65 to 69 years old to 0.86 and 76, respectively, in ≥85 years old subjects. Increasing age, female gender, low education, geographic factors and comorbidities were associated with impaired health status. Conclusions: Within community-dwelling elderly large differences in health status exist. Impairment increases rapidly with age, but health status is also associated with socio-demographic variables and comorbidities. Trial registration: ClinicalTrials.gov, NCT00812084.

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JO - Health and Quality of Life Outcomes

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Quality of life in community-dwelling Dutch elderly measured by EQ-5D-3L

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