Quantitative and temporal approach to utilising electronic medical records from general practices in mental health prediction

Olga Półchłopek*, Nynke R. Koning, Frederike L. Büchner, Mathilde R. Crone, Mattijs E. Numans, Mark Hoogendoorn

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

This study proposes a framework for mining temporal patterns from Electronic Medical Records. A new scoring scheme based on the Wilson interval is provided to obtain frequent and predictive patterns, as well as to accelerate the mining process by reducing the number of patterns mined. This is combined with a case study using data from general practices in the Netherlands to identify children at risk of suffering from mental disorders. To develop an accurate model, feature engineering methods such as one hot encoding and frequency transformation are proposed, and the pattern selection is tailored to this type of clinical data. Six machine learning models are trained on five age groups, with XGBoost achieving the highest AUC values (0.75–0.79) with sensitivity and specificity above 0.7 and 0.6 respectively. An improvement is demonstrated by the models learning from patterns in addition to non-temporal features.

Original languageEnglish
Article number103973
Pages (from-to)1-15
Number of pages15
JournalComputers in Biology and Medicine
Volume125
Early online date18 Aug 2020
DOIs
Publication statusPublished - Oct 2020

Funding

This work was supported by ZonMW, the Netherlands, Organization for Health Research and Development (grant 839110012 ).

Keywords

  • Electronic medical records
  • General practice
  • Mental health classification
  • Pattern recognition
  • Temporal pattern mining

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