Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

P. Zanoni; S.A. Khetarpal; D.B. Larach; W.F. Hancock-Cerutti; J.S. Millar; M. Cuchel; S. DerOhannessian; A. Kontush; P. Surendran; D. Saleheen; S. Trompet; J.W. Jukema; A.J.M. Craen; P. Deloukas; N. Sattar; I. Ford; C. Packard; A. Majumder; D.S. Alam; E. Di Angelantonio; G. Abecasis; R. Chowdhury; J. Erdmann; B.G. Nordestgaard; S.F. Nielsen; A. Tybjærg-Hansen; R.F. Schmidt; K. Kuulasmaa; D.J. Liu; M. Perola; S. Blankenberg; V. Salomaa; S. Männistö; P. Amouyel; D. Arveiler; J. Ferrières; M. Müller-Nurasyid; M.M. Ferrario; F Kee; C.J. Willer; N. Samani; H. Schunkert; A.S. Butterworth; J.M. Howson; G.M. Peloso; N.O. Stitziel; J. Danesh; S. Kathiresan; D.J. Rader; G. Willemsen; D.I. Boomsma

doi:10.1126/science.aad3517

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

P. Zanoni, S.A. Khetarpal, D.B. Larach, W.F. Hancock-Cerutti, J.S. Millar, M. Cuchel, S. DerOhannessian, A. Kontush, P. Surendran, D. Saleheen, S. Trompet, J.W. Jukema, A.J.M. Craen, P. Deloukas, N. Sattar, I. Ford, C. Packard, A. Majumder, D.S. Alam, E. Di AngelantonioG. Abecasis, R. Chowdhury, J. Erdmann, B.G. Nordestgaard, S.F. Nielsen, A. Tybjærg-Hansen, R.F. Schmidt, K. Kuulasmaa, D.J. Liu, M. Perola, S. Blankenberg, V. Salomaa, S. Männistö, P. Amouyel, D. Arveiler, J. Ferrières, M. Müller-Nurasyid, M.M. Ferrario, F Kee, C.J. Willer, N. Samani, H. Schunkert, A.S. Butterworth, J.M. Howson, G.M. Peloso, N.O. Stitziel, J. Danesh, S. Kathiresan, D.J. Rader, G. Willemsen, D.I. Boomsma

Biological Psychology

Research output: Contribution to Journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1166-1171
Journal	Science
Volume	351
Issue number	6278
DOIs	https://doi.org/10.1126/science.aad3517
Publication status	Published - 2016

Cohort Studies

Netherlands Twin Register (NTR)

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Zanoni, P., Khetarpal, S. A., Larach, D. B., Hancock-Cerutti, W. F., Millar, J. S., Cuchel, M., DerOhannessian, S., Kontush, A., Surendran, P., Saleheen, D., Trompet, S., Jukema, J. W., Craen, A. J. M., Deloukas, P., Sattar, N., Ford, I., Packard, C., Majumder, A., Alam, D. S., ... Boomsma, D. I. (2016). Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. Science, 351(6278), 1166-1171. https://doi.org/10.1126/science.aad3517

@article{fe976ca42b114b359d11c01575d1e4f9,

title = "Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease",

author = "P. Zanoni and S.A. Khetarpal and D.B. Larach and W.F. Hancock-Cerutti and J.S. Millar and M. Cuchel and S. DerOhannessian and A. Kontush and P. Surendran and D. Saleheen and S. Trompet and J.W. Jukema and A.J.M. Craen and P. Deloukas and N. Sattar and I. Ford and C. Packard and A. Majumder and D.S. Alam and {Di Angelantonio}, E. and G. Abecasis and R. Chowdhury and J. Erdmann and B.G. Nordestgaard and S.F. Nielsen and A. Tybj{\ae}rg-Hansen and R.F. Schmidt and K. Kuulasmaa and D.J. Liu and M. Perola and S. Blankenberg and V. Salomaa and S. M{\"a}nnist{\"o} and P. Amouyel and D. Arveiler and J. Ferri{\`e}res and M. M{\"u}ller-Nurasyid and M.M. Ferrario and F Kee and C.J. Willer and N. Samani and H. Schunkert and A.S. Butterworth and J.M. Howson and G.M. Peloso and N.O. Stitziel and J. Danesh and S. Kathiresan and D.J. Rader and G. Willemsen and D.I. Boomsma",

year = "2016",

doi = "10.1126/science.aad3517",

language = "English",

volume = "351",

pages = "1166--1171",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "6278",

}

Zanoni, P, Khetarpal, SA, Larach, DB, Hancock-Cerutti, WF, Millar, JS, Cuchel, M, DerOhannessian, S, Kontush, A, Surendran, P, Saleheen, D, Trompet, S, Jukema, JW, Craen, AJM, Deloukas, P, Sattar, N, Ford, I, Packard, C, Majumder, A, Alam, DS, Di Angelantonio, E, Abecasis, G, Chowdhury, R, Erdmann, J, Nordestgaard, BG, Nielsen, SF, Tybjærg-Hansen, A, Schmidt, RF, Kuulasmaa, K, Liu, DJ, Perola, M, Blankenberg, S, Salomaa, V, Männistö, S, Amouyel, P, Arveiler, D, Ferrières, J, Müller-Nurasyid, M, Ferrario, MM, Kee, F, Willer, CJ, Samani, N, Schunkert, H, Butterworth, AS, Howson, JM, Peloso, GM, Stitziel, NO, Danesh, J, Kathiresan, S, Rader, DJ, Willemsen, G & Boomsma, DI 2016, 'Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease', Science, vol. 351, no. 6278, pp. 1166-1171. https://doi.org/10.1126/science.aad3517

TY - JOUR

T1 - Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

AU - Zanoni, P.

AU - Khetarpal, S.A.

AU - Larach, D.B.

AU - Hancock-Cerutti, W.F.

AU - Millar, J.S.

AU - Cuchel, M.

AU - DerOhannessian, S.

AU - Kontush, A.

AU - Surendran, P.

AU - Saleheen, D.

AU - Trompet, S.

AU - Jukema, J.W.

AU - Craen, A.J.M.

AU - Deloukas, P.

AU - Sattar, N.

AU - Ford, I.

AU - Packard, C.

AU - Majumder, A.

AU - Alam, D.S.

AU - Di Angelantonio, E.

AU - Abecasis, G.

AU - Chowdhury, R.

AU - Erdmann, J.

AU - Nordestgaard, B.G.

AU - Nielsen, S.F.

AU - Tybjærg-Hansen, A.

AU - Schmidt, R.F.

AU - Kuulasmaa, K.

AU - Liu, D.J.

AU - Perola, M.

AU - Blankenberg, S.

AU - Salomaa, V.

AU - Männistö, S.

AU - Amouyel, P.

AU - Arveiler, D.

AU - Ferrières, J.

AU - Müller-Nurasyid, M.

AU - Ferrario, M.M.

AU - Kee, F

AU - Willer, C.J.

AU - Samani, N.

AU - Schunkert, H.

AU - Butterworth, A.S.

AU - Howson, J.M.

AU - Peloso, G.M.

AU - Stitziel, N.O.

AU - Danesh, J.

AU - Kathiresan, S.

AU - Rader, D.J.

AU - Willemsen, G.

AU - Boomsma, D.I.

PY - 2016

Y1 - 2016

U2 - 10.1126/science.aad3517

DO - 10.1126/science.aad3517

M3 - Article

SN - 0036-8075

VL - 351

SP - 1166

EP - 1171

JO - Science

JF - Science

IS - 6278

ER -