Recent advances in capillary electrophoretic migration techniques for pharmaceutical analysis

Sami El Deeb, Hermann Wätzig, Deia Abd El-Hady, Hassan M. Albishri, Cari Sänger van de Griend, Gerhard K E Scriba

Research output: Contribution to JournalReview articleAcademicpeer-review

Abstract

Since the introduction about 30 years ago, CE techniques have gained a significant impact in pharmaceutical analysis. The present review covers recent advances and applications of CE for the analysis of pharmaceuticals. Both small molecules and biomolecules such as proteins are considered. The applications range from the determination of drug-related substances to the analysis of counterions and the determination of physicochemical parameters. Furthermore, general considerations of CE methods in pharmaceutical analysis are described.

Original languageEnglish
Pages (from-to)170-189
Number of pages20
JournalElectrophoresis
Volume35
Issue number1
DOIs
Publication statusPublished - Jan 2014
Externally publishedYes

Keywords

  • Biopharmaceuticals
  • CE
  • Pharmaceutical analysis
  • Quantitation

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