Recent advances in understanding the ecology of the lung microbiota and deciphering the gut-lung axis

Kent A. Willis*, Justin D. Stewart, Namasivayam Ambalavanan

*Corresponding author for this work

Research output: Contribution to JournalReview articleAcademicpeer-review

Abstract

A rapidly expanding new field of lung research has been produced by the emergence of culture-independent next-generation sequencing technologies. While pulmonary microbiome research lags behind the exploration of the microbiome in other organ systems, the field is maturing and has recently produced multiple exciting discoveries. In this mini-review, we will explore recent advances in our understanding of the lung microbiome and the gut-lung axis from an ecological perspective.

Original languageEnglish
Pages (from-to)L710-L716
Number of pages7
JournalAmerican Journal of Physiology - Lung Cellular and Molecular Physiology
Volume319
Issue number4
Early online date6 Oct 2020
DOIs
Publication statusPublished - Oct 2020
Externally publishedYes

Funding

This work was supported in part by NIH National Heart, Lung, and Blood Institute (NHLBI) Grant K08HL151907 (K.A.W.), The University of Alabama at Birmingham (UAB) Microbiome Center (K.A.W.), and NHLBI Grants U01HL133536 and R01HL129907 (N.A.).

FundersFunder number
National Heart, Lung, and Blood InstituteK08HL151907, U01HL133536, R01HL129907
University of Alabama

    Keywords

    • Bacteria
    • Bronchopulmonary dysplasia
    • Fungi
    • Microbiome
    • Mycobiome

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