Reduction in energy expenditure during weight loss is higher than predicted based on fat free mass and fat mass in older adults

T.P.G. ten Haaf, A.M. Verreijen, R.G. Memelink, M. Tieland, P.J.M. Weijs

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Background & aim: The aim of this study was to describe a decrease in resting energy expenditure during weight loss that is larger than expected based on changes in body composition, called adaptive thermogenesis (AT), in overweight and obese older adults. Methods: Multiple studies were combined to assess AT in younger and older subjects. Body composition and resting energy expenditure (REE) were measured before and after weight loss. Baseline values were used to predict fat free mass and fat mass adjusted REE after weight loss. AT was defined as the difference between predicted and measured REE after weight loss. The median age of 55 y was used as a cutoff to compare older with younger subjects. The relation between AT and age was investigated using linear regression analysis. Results: In this study 254 (M = 88, F = 166) overweight and obese subjects were included (BMI: 31.7 ± 4.4 kg/m
Original languageEnglish
Pages (from-to)250-253
JournalClinical Nutrition
Volume37
Issue number1
DOIs
Publication statusPublished - Feb 2018

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Thermogenesis
Energy Metabolism
Weight Loss
Fats
Body Composition
Linear Models
Regression Analysis

Cite this

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title = "Reduction in energy expenditure during weight loss is higher than predicted based on fat free mass and fat mass in older adults",
abstract = "Background & aim: The aim of this study was to describe a decrease in resting energy expenditure during weight loss that is larger than expected based on changes in body composition, called adaptive thermogenesis (AT), in overweight and obese older adults. Methods: Multiple studies were combined to assess AT in younger and older subjects. Body composition and resting energy expenditure (REE) were measured before and after weight loss. Baseline values were used to predict fat free mass and fat mass adjusted REE after weight loss. AT was defined as the difference between predicted and measured REE after weight loss. The median age of 55 y was used as a cutoff to compare older with younger subjects. The relation between AT and age was investigated using linear regression analysis. Results: In this study 254 (M = 88, F = 166) overweight and obese subjects were included (BMI: 31.7 ± 4.4 kg/m",
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Reduction in energy expenditure during weight loss is higher than predicted based on fat free mass and fat mass in older adults. / ten Haaf, T.P.G.; Verreijen, A.M.; Memelink, R.G.; Tieland, M.; Weijs, P.J.M.

In: Clinical Nutrition, Vol. 37, No. 1, 02.2018, p. 250-253.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - Reduction in energy expenditure during weight loss is higher than predicted based on fat free mass and fat mass in older adults

AU - ten Haaf, T.P.G.

AU - Verreijen, A.M.

AU - Memelink, R.G.

AU - Tieland, M.

AU - Weijs, P.J.M.

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AB - Background & aim: The aim of this study was to describe a decrease in resting energy expenditure during weight loss that is larger than expected based on changes in body composition, called adaptive thermogenesis (AT), in overweight and obese older adults. Methods: Multiple studies were combined to assess AT in younger and older subjects. Body composition and resting energy expenditure (REE) were measured before and after weight loss. Baseline values were used to predict fat free mass and fat mass adjusted REE after weight loss. AT was defined as the difference between predicted and measured REE after weight loss. The median age of 55 y was used as a cutoff to compare older with younger subjects. The relation between AT and age was investigated using linear regression analysis. Results: In this study 254 (M = 88, F = 166) overweight and obese subjects were included (BMI: 31.7 ± 4.4 kg/m

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