TY - JOUR
T1 - Response to a wild poliovirus type 2 (WPV2)-shedding event following accidental exposure to WPV2, the Netherlands, April 2017
AU - Duizer, Erwin
AU - Ruijs, Wilhelmina Lm
AU - van der Weijden, Charlie P
AU - Timen, Aura
N1 - This article is copyright of The Authors, 2017.
PY - 2017/5/25
Y1 - 2017/5/25
N2 - On 3 April 2017, a wild poliovirus type 2 (WPV2) spill occurred in a Dutch vaccine manufacturing plant. Two fully vaccinated operators with risk of exposure were advised on stringent personal hygiene and were monitored for virus shedding. Poliovirus (WPV2-MEF1) was detected in the stool of one, 4 days after exposure, later also in sewage samples. The operator was isolated at home and followed up until shedding stopped 29 days after exposure. No further transmission was detected.
AB - On 3 April 2017, a wild poliovirus type 2 (WPV2) spill occurred in a Dutch vaccine manufacturing plant. Two fully vaccinated operators with risk of exposure were advised on stringent personal hygiene and were monitored for virus shedding. Poliovirus (WPV2-MEF1) was detected in the stool of one, 4 days after exposure, later also in sewage samples. The operator was isolated at home and followed up until shedding stopped 29 days after exposure. No further transmission was detected.
KW - Containment of Biohazards
KW - Environmental Monitoring/methods
KW - Feces/virology
KW - Humans
KW - Netherlands/epidemiology
KW - Poliomyelitis/prevention & control
KW - Poliovirus Vaccine, Oral/administration & dosage
KW - Poliovirus/isolation & purification
KW - Risk Assessment/methods
KW - Risk Management/methods
KW - Sewage
KW - Virus Shedding
KW - Water Microbiology
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U2 - 10.2807/1560-7917.ES.2017.22.21.30542
DO - 10.2807/1560-7917.ES.2017.22.21.30542
M3 - Article
C2 - 28597830
SN - 1025-496X
VL - 22
JO - Euro Surveill
JF - Euro Surveill
IS - 21
ER -