Response to imported case of Marburg hemorrhagic fever, the Netherland

Aura Timen, Marion P G Koopmans, Ann C T M Vossen, Gerard J J van Doornum, Stephan Günther, Franchette van den Berkmortel, Kees M Verduin, Sabine Dittrich, Petra Emmerich, Albert D M E Osterhaus, Jaap T van Dissel, Roel A Coutinho

Research output: Contribution to JournalArticleAcademicpeer-review


On July 10, 2008, Marburg hemorrhagic fever was confirmed in a Dutch patient who had vacationed recently in Uganda. Exposure most likely occurred in the Python Cave (Maramagambo Forest), which harbors bat species that elsewhere in Africa have been found positive for Marburg virus. A multidisciplinary response team was convened to perform a structured risk assessment, perform risk classification of contacts, issue guidelines for follow-up, provide information, and monitor the crisis response. In total, 130 contacts were identified (66 classified as high risk and 64 as low risk) and monitored for 21 days after their last possible exposure. The case raised questions specific to international travel, postexposure prophylaxis for Marburg virus, and laboratory testing of contacts with fever. We present lessons learned and results of the follow-up serosurvey of contacts and focus on factors that prevented overreaction during an event with a high public health impact.

Original languageEnglish
Pages (from-to)1171-5
Number of pages5
JournalEmerging Infectious Diseases
Issue number8
Publication statusPublished - Aug 2009
Externally publishedYes


  • Adult
  • Animals
  • Chiroptera/virology
  • Communicable Diseases, Emerging/diagnosis
  • Contact Tracing
  • Disease Reservoirs
  • Female
  • Humans
  • Marburg Virus Disease/diagnosis
  • Netherlands
  • Public Health
  • Travel
  • Uganda/ethnology


Dive into the research topics of 'Response to imported case of Marburg hemorrhagic fever, the Netherland'. Together they form a unique fingerprint.

Cite this