TY - JOUR
T1 - Ribosome synthesis in Saccharomyces cerevisiae
AU - Venema, J.
AU - Tollervey, D.
PY - 1999
Y1 - 1999
N2 - The synthesis of ribosomes is one of the major metabolic pathways in all cells. In addition to around 75 individual ribosomal proteins and 4 ribosomal RNAs, synthesis of a functional eukaryotic ribosome requires a remarkable number of trans-acting factors. Here, we will discuss the recent, and often surprising, advances in our understanding of ribosome synthesis in the yeast Saccharomyces cerevisiae. These will underscore the unexpected complexity of eukaryotic ribosome synthesis.
AB - The synthesis of ribosomes is one of the major metabolic pathways in all cells. In addition to around 75 individual ribosomal proteins and 4 ribosomal RNAs, synthesis of a functional eukaryotic ribosome requires a remarkable number of trans-acting factors. Here, we will discuss the recent, and often surprising, advances in our understanding of ribosome synthesis in the yeast Saccharomyces cerevisiae. These will underscore the unexpected complexity of eukaryotic ribosome synthesis.
UR - https://www.scopus.com/pages/publications/0033367325
UR - https://www.scopus.com/inward/citedby.url?scp=0033367325&partnerID=8YFLogxK
U2 - 10.1146/annurev.genet.33.1.261
DO - 10.1146/annurev.genet.33.1.261
M3 - Article
SN - 0066-4197
VL - 33
SP - 261
EP - 311
JO - Annual Review of Genetics
JF - Annual Review of Genetics
ER -