Role of extracellular DNA in initial bacterial adhesion and surface aggregation

Theerthankar Das; Prashant K Sharma; Henk J Busscher; Henny C van der Mei; Bastiaan P Krom

doi:10.1128/AEM.03119-09

Role of extracellular DNA in initial bacterial adhesion and surface aggregation

Theerthankar Das, Prashant K Sharma, Henk J Busscher, Henny C van der Mei, Bastiaan P Krom

Preventive Dentistry

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Extracellular DNA (eDNA) is an important component of the biofilm matrix. We show that removal of eDNA from Gram-positive bacteria reduces initial adhesion to and aggregation of bacteria on surfaces. Thermodynamic analyses indicated that eDNA introduces favorable acid-base interactions, explaining the effect of eDNA on aggregation and adhesion to the surface.

Original language	English
Pages (from-to)	3405-8
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	76
Issue number	10
DOIs	https://doi.org/10.1128/AEM.03119-09
Publication status	Published - May 2010

Keywords

Bacterial Adhesion/genetics
Biofilms
DNA/metabolism
Gram-Positive Bacteria/genetics
Hydrophobic and Hydrophilic Interactions
Mutation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/AEM.03119-09

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title = "Role of extracellular DNA in initial bacterial adhesion and surface aggregation",

abstract = "Extracellular DNA (eDNA) is an important component of the biofilm matrix. We show that removal of eDNA from Gram-positive bacteria reduces initial adhesion to and aggregation of bacteria on surfaces. Thermodynamic analyses indicated that eDNA introduces favorable acid-base interactions, explaining the effect of eDNA on aggregation and adhesion to the surface.",

keywords = "Bacterial Adhesion/genetics, Biofilms, DNA/metabolism, Gram-Positive Bacteria/genetics, Hydrophobic and Hydrophilic Interactions, Mutation",

author = "Theerthankar Das and Sharma, \{Prashant K\} and Busscher, \{Henk J\} and \{van der Mei\}, \{Henny C\} and Krom, \{Bastiaan P\}",

year = "2010",

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doi = "10.1128/AEM.03119-09",

language = "English",

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AU - Das, Theerthankar

AU - Sharma, Prashant K

AU - Busscher, Henk J

AU - van der Mei, Henny C

AU - Krom, Bastiaan P

PY - 2010/5

Y1 - 2010/5

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AB - Extracellular DNA (eDNA) is an important component of the biofilm matrix. We show that removal of eDNA from Gram-positive bacteria reduces initial adhesion to and aggregation of bacteria on surfaces. Thermodynamic analyses indicated that eDNA introduces favorable acid-base interactions, explaining the effect of eDNA on aggregation and adhesion to the surface.

KW - Bacterial Adhesion/genetics

KW - Biofilms

KW - DNA/metabolism

KW - Gram-Positive Bacteria/genetics

KW - Hydrophobic and Hydrophilic Interactions

KW - Mutation

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DO - 10.1128/AEM.03119-09

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SN - 0099-2240

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EP - 3408

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 10

ER -

Role of extracellular DNA in initial bacterial adhesion and surface aggregation

Abstract

Keywords

UN SDGs

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