TY - JOUR
T1 - S-adenosylhomocysteine and the ratio of S-adenosylmethionine to S-adenosylhomocysteine are not related to folate, cobalamin and vitamin B6 concentrations
AU - Becker, A.
AU - Smulders, Y.M.
AU - Teerlink, T.
AU - Struys, E.A.
AU - de Meer, K.
AU - Kostense, P.J.
AU - Jakobs, C.
AU - Dekker, J.M.
AU - Nijpels, G.
AU - Heine, R.J.
AU - Bouter, L.M.
AU - Stehouwer, C.D.A.
PY - 2003
Y1 - 2003
N2 - Background: It is unclear whether homocysteine itself is causal in the pathogenesis of cardiovascular disease. Alternatively or additionally, the association between homocysteine and cardiovascular disease may be because of its metabolic precursor, S-adenosylhomocysteine, or of the ratio of S-adenosylmethionine to S-adenosylhomocysteine. Therefore, it is relevant to know how these moieties are interrelated, and whether, as is the case for homocysteine, they are influenced by blood levels of folate, cobalamin or vitamin B
AB - Background: It is unclear whether homocysteine itself is causal in the pathogenesis of cardiovascular disease. Alternatively or additionally, the association between homocysteine and cardiovascular disease may be because of its metabolic precursor, S-adenosylhomocysteine, or of the ratio of S-adenosylmethionine to S-adenosylhomocysteine. Therefore, it is relevant to know how these moieties are interrelated, and whether, as is the case for homocysteine, they are influenced by blood levels of folate, cobalamin or vitamin B
U2 - 10.1046/j.1365-2362.2003.01104.x
DO - 10.1046/j.1365-2362.2003.01104.x
M3 - Article
SN - 0014-2972
VL - 33
SP - 17
EP - 25
JO - European Journal of Clinical Investigation
JF - European Journal of Clinical Investigation
IS - 1
ER -
