Sarcopenia: Revised European consensus on definition and diagnosis

Alfonso J. Cruz-Jentoft, Gülistan Bahat, Jürgen Bauer, Yves Boirie, Olivier Bruyère, Tommy Cederholm, Cyrus Cooper, Francesco Landi, Yves Rolland, Avan Aihie Sayer, Stéphane M. Schneider, Cornel C. Sieber, Eva Topinkova, Maurits Vandewoude, Marjolein Visser, Mauro Zamboni, Ivan Bautmans, Jean Pierre Baeyens, Matteo Cesari, Antonio Cherubini & 9 others John Kanis, Marcello Maggio, Finbarr Martin, Jean Pierre Michel, Kaisu Pitkala, Jean Yves Reginster, René Rizzoli, Dolores Sánchez-Rodríguez, Jos Schols

Research output: Contribution to JournalReview articleAcademicpeer-review

Abstract

Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.

Original languageEnglish
Pages (from-to)16-31
Number of pages16
JournalAge and Ageing
Volume48
Issue number1
Early online date24 Sep 2018
DOIs
Publication statusPublished - Jan 2019

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Sarcopenia
Consensus
Muscles
Delivery of Health Care
Muscle Strength

Keywords

  • EWGSOP2
  • muscle assessment
  • muscle strength
  • older people
  • physical performance
  • sarcopenia

Cite this

Cruz-Jentoft, A. J., Bahat, G., Bauer, J., Boirie, Y., Bruyère, O., Cederholm, T., ... Schols, J. (2019). Sarcopenia: Revised European consensus on definition and diagnosis. Age and Ageing, 48(1), 16-31. https://doi.org/10.1093/ageing/afy169
Cruz-Jentoft, Alfonso J. ; Bahat, Gülistan ; Bauer, Jürgen ; Boirie, Yves ; Bruyère, Olivier ; Cederholm, Tommy ; Cooper, Cyrus ; Landi, Francesco ; Rolland, Yves ; Sayer, Avan Aihie ; Schneider, Stéphane M. ; Sieber, Cornel C. ; Topinkova, Eva ; Vandewoude, Maurits ; Visser, Marjolein ; Zamboni, Mauro ; Bautmans, Ivan ; Baeyens, Jean Pierre ; Cesari, Matteo ; Cherubini, Antonio ; Kanis, John ; Maggio, Marcello ; Martin, Finbarr ; Michel, Jean Pierre ; Pitkala, Kaisu ; Reginster, Jean Yves ; Rizzoli, René ; Sánchez-Rodríguez, Dolores ; Schols, Jos. / Sarcopenia : Revised European consensus on definition and diagnosis. In: Age and Ageing. 2019 ; Vol. 48, No. 1. pp. 16-31.
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Cruz-Jentoft, AJ, Bahat, G, Bauer, J, Boirie, Y, Bruyère, O, Cederholm, T, Cooper, C, Landi, F, Rolland, Y, Sayer, AA, Schneider, SM, Sieber, CC, Topinkova, E, Vandewoude, M, Visser, M, Zamboni, M, Bautmans, I, Baeyens, JP, Cesari, M, Cherubini, A, Kanis, J, Maggio, M, Martin, F, Michel, JP, Pitkala, K, Reginster, JY, Rizzoli, R, Sánchez-Rodríguez, D & Schols, J 2019, 'Sarcopenia: Revised European consensus on definition and diagnosis' Age and Ageing, vol. 48, no. 1, pp. 16-31. https://doi.org/10.1093/ageing/afy169

Sarcopenia : Revised European consensus on definition and diagnosis. / Cruz-Jentoft, Alfonso J.; Bahat, Gülistan; Bauer, Jürgen; Boirie, Yves; Bruyère, Olivier; Cederholm, Tommy; Cooper, Cyrus; Landi, Francesco; Rolland, Yves; Sayer, Avan Aihie; Schneider, Stéphane M.; Sieber, Cornel C.; Topinkova, Eva; Vandewoude, Maurits; Visser, Marjolein; Zamboni, Mauro; Bautmans, Ivan; Baeyens, Jean Pierre; Cesari, Matteo; Cherubini, Antonio; Kanis, John; Maggio, Marcello; Martin, Finbarr; Michel, Jean Pierre; Pitkala, Kaisu; Reginster, Jean Yves; Rizzoli, René; Sánchez-Rodríguez, Dolores; Schols, Jos.

In: Age and Ageing, Vol. 48, No. 1, 01.2019, p. 16-31.

Research output: Contribution to JournalReview articleAcademicpeer-review

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T1 - Sarcopenia

T2 - Revised European consensus on definition and diagnosis

AU - Cruz-Jentoft, Alfonso J.

AU - Bahat, Gülistan

AU - Bauer, Jürgen

AU - Boirie, Yves

AU - Bruyère, Olivier

AU - Cederholm, Tommy

AU - Cooper, Cyrus

AU - Landi, Francesco

AU - Rolland, Yves

AU - Sayer, Avan Aihie

AU - Schneider, Stéphane M.

AU - Sieber, Cornel C.

AU - Topinkova, Eva

AU - Vandewoude, Maurits

AU - Visser, Marjolein

AU - Zamboni, Mauro

AU - Bautmans, Ivan

AU - Baeyens, Jean Pierre

AU - Cesari, Matteo

AU - Cherubini, Antonio

AU - Kanis, John

AU - Maggio, Marcello

AU - Martin, Finbarr

AU - Michel, Jean Pierre

AU - Pitkala, Kaisu

AU - Reginster, Jean Yves

AU - Rizzoli, René

AU - Sánchez-Rodríguez, Dolores

AU - Schols, Jos

PY - 2019/1

Y1 - 2019/1

N2 - Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.

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KW - physical performance

KW - sarcopenia

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Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T et al. Sarcopenia: Revised European consensus on definition and diagnosis. Age and Ageing. 2019 Jan;48(1):16-31. https://doi.org/10.1093/ageing/afy169