Self-Reported Fatigue and Energy Cost During Walking Are Not Related in Patients With Multiple Sclerosis

J.C.E. Kempen, V. de Groot, D.L. Knol, G.J. Lankhorst, H. Beckerman

    Research output: Contribution to JournalArticleAcademicpeer-review


    Objectives: To determine whether there is a relationship between self-reported fatigue and the energy cost of walking (ECw), and how self-reported fatigue and ECw relate to physical functioning in patients with multiple sclerosis (MS). Design: Cross-sectional cohort study, using structural equation modeling. Setting: Home environment and at a university medical center. Participants: Patients (N=75) were obtained from a longitudinal study on outcome measurement and functional prognosis in early MS. Patients were included if they were able to walk for 6 minutes without being assisted by a person. The age range was between 28.0 and 69.7 years and the median Expanded Disability Status Scale was 2.5 (range, 1.0-6.5). Interventions: Not applicable. Main Outcome Measures: Self-reported fatigue was measured with the Fatigue Severity Scale, the vitality subscale of the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36), and a visual analog scale. Physical functioning was determined with the physical functioning subscale of the SF-36, fast walking speed, and comfortable walking speed. The ECw (J·kg
    Original languageEnglish
    Pages (from-to)889-895
    JournalArchives of Physical Medicine and Rehabilitation
    Issue number5
    Publication statusPublished - 2012


    Dive into the research topics of 'Self-Reported Fatigue and Energy Cost During Walking Are Not Related in Patients With Multiple Sclerosis'. Together they form a unique fingerprint.

    Cite this