Sensory Function and Chronic Pain in Multiple Sclerosis

Rogier J. Scherder, Neeltje Kant, Evelien T. Wolf, Bas C.M. Pijnenburg, Erik J.A. Scherder

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Objective. To examine whether hypoesthesia and chronic pain are related in patients with MS. Methods. Sixty-seven MS patients with pain and 80 persons without MS were included. Sensory functioning was tested by bedside neurological examination. Touch, joint position (dorsal column-medial lemniscus pathway), temperature sense, and pain (spinothalamic tract) were tested. Pain intensity was measured by the Colored Analogue Scale (CAS Intensity) and the Faces Pain Scale (FPS); pain affect was also measured by CAS Affect and Number of Words Chosen-Affective (NWC-A). Mood was assessed with the SCL-90 anxiety and depression subscales and the Beck Depression Inventory (BDI). Results. A significant negative relationship was found between pain intensity and the function of the dorsal column-medial lemniscal pathway, but not with the spinothalamic tract. Conclusion. In addition to the already known relation between hyperesthesia and pain, hypoesthesia for touch and joint position also seems to be related to chronic pain in MS patients.

Original languageEnglish
Article number1924174
Pages (from-to)1-10
Number of pages10
JournalPain Research and Management
Volume2018
DOIs
Publication statusPublished - 23 Apr 2018

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Chronic Pain
Multiple Sclerosis
Pain
Spinothalamic Tracts
Hypesthesia
Touch
Thermosensing
Joints
Hyperesthesia
Depression
Facial Pain
Supine Position
Neurologic Examination
Anxiety
Equipment and Supplies

Cite this

Scherder, R. J., Kant, N., Wolf, E. T., Pijnenburg, B. C. M., & Scherder, E. J. A. (2018). Sensory Function and Chronic Pain in Multiple Sclerosis. Pain Research and Management, 2018, 1-10. [1924174]. https://doi.org/10.1155/2018/1924174
Scherder, Rogier J. ; Kant, Neeltje ; Wolf, Evelien T. ; Pijnenburg, Bas C.M. ; Scherder, Erik J.A. / Sensory Function and Chronic Pain in Multiple Sclerosis. In: Pain Research and Management. 2018 ; Vol. 2018. pp. 1-10.
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Scherder, RJ, Kant, N, Wolf, ET, Pijnenburg, BCM & Scherder, EJA 2018, 'Sensory Function and Chronic Pain in Multiple Sclerosis' Pain Research and Management, vol. 2018, 1924174, pp. 1-10. https://doi.org/10.1155/2018/1924174

Sensory Function and Chronic Pain in Multiple Sclerosis. / Scherder, Rogier J.; Kant, Neeltje; Wolf, Evelien T.; Pijnenburg, Bas C.M.; Scherder, Erik J.A.

In: Pain Research and Management, Vol. 2018, 1924174, 23.04.2018, p. 1-10.

Research output: Contribution to JournalArticleAcademicpeer-review

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N2 - Objective. To examine whether hypoesthesia and chronic pain are related in patients with MS. Methods. Sixty-seven MS patients with pain and 80 persons without MS were included. Sensory functioning was tested by bedside neurological examination. Touch, joint position (dorsal column-medial lemniscus pathway), temperature sense, and pain (spinothalamic tract) were tested. Pain intensity was measured by the Colored Analogue Scale (CAS Intensity) and the Faces Pain Scale (FPS); pain affect was also measured by CAS Affect and Number of Words Chosen-Affective (NWC-A). Mood was assessed with the SCL-90 anxiety and depression subscales and the Beck Depression Inventory (BDI). Results. A significant negative relationship was found between pain intensity and the function of the dorsal column-medial lemniscal pathway, but not with the spinothalamic tract. Conclusion. In addition to the already known relation between hyperesthesia and pain, hypoesthesia for touch and joint position also seems to be related to chronic pain in MS patients.

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