Short psychodynamic supportive psychotherapy, antidepressants, and their combination in the treatment of major depression: A mega-analysis based on three randomized clinical trials

S.C.M. de Maat; J.J.M. Dekker; R.A. Schoevers; G. van Aalst; C.G. Natijk; M. Hendriksen; S. Kool; J. Peen; R. Van; F. de Jonghe

doi:10.1002/da.20305

Short psychodynamic supportive psychotherapy, antidepressants, and their combination in the treatment of major depression: A mega-analysis based on three randomized clinical trials

S.C.M. de Maat, J.J.M. Dekker, R.A. Schoevers, G. van Aalst, C.G. Natijk, M. Hendriksen, S. Kool, J. Peen, R. Van, F. de Jonghe

Clinical Psychology

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Abstract

The efficacy of Short Psychodynamic Supportive Psychotherapy (SPSP) has not yet been compared with pharmacotherapy. A mega-analysis based on three original Randomized Clinical Trials (RCTs) was performed. Patients with (mild to moderate) major depressive disorder were randomized in (24 weeks) SPSP (n = 97), pharmacotherapy (n = 45), or their combination (n = 171). Efficacy was assessed by the Hamilton Depression Rating Scale (HDRS), Clinical Global Impression of Severity and of Improvement (CGI-S), the Symptom Checklist (SCL; depression subscale) and the Quality of Life Depression Scale (QLDS). Pearson χ

Original language	English
Pages (from-to)	565-574
Journal	Depression and Anxiety
Volume	25
Issue number	7
DOIs	https://doi.org/10.1002/da.20305
Publication status	Published - 2008

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de Maat, S. C. M., Dekker, J. J. M., Schoevers, R. A., van Aalst, G., Natijk, C. G., Hendriksen, M., Kool, S., Peen, J., Van, R., & de Jonghe, F. (2008). Short psychodynamic supportive psychotherapy, antidepressants, and their combination in the treatment of major depression: A mega-analysis based on three randomized clinical trials. Depression and Anxiety, 25(7), 565-574. https://doi.org/10.1002/da.20305

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title = "Short psychodynamic supportive psychotherapy, antidepressants, and their combination in the treatment of major depression: A mega-analysis based on three randomized clinical trials",

abstract = "The efficacy of Short Psychodynamic Supportive Psychotherapy (SPSP) has not yet been compared with pharmacotherapy. A mega-analysis based on three original Randomized Clinical Trials (RCTs) was performed. Patients with (mild to moderate) major depressive disorder were randomized in (24 weeks) SPSP (n = 97), pharmacotherapy (n = 45), or their combination (n = 171). Efficacy was assessed by the Hamilton Depression Rating Scale (HDRS), Clinical Global Impression of Severity and of Improvement (CGI-S), the Symptom Checklist (SCL; depression subscale) and the Quality of Life Depression Scale (QLDS). Pearson χ",

author = "{de Maat}, S.C.M. and J.J.M. Dekker and R.A. Schoevers and {van Aalst}, G. and C.G. Natijk and M. Hendriksen and S. Kool and J. Peen and R. Van and {de Jonghe}, F.",

year = "2008",

doi = "10.1002/da.20305",

language = "English",

volume = "25",

pages = "565--574",

journal = "Depression and Anxiety",

issn = "1091-4269",

publisher = "Wiley-Blackwell",

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de Maat, SCM, Dekker, JJM, Schoevers, RA, van Aalst, G, Natijk, CG, Hendriksen, M, Kool, S, Peen, J, Van, R & de Jonghe, F 2008, 'Short psychodynamic supportive psychotherapy, antidepressants, and their combination in the treatment of major depression: A mega-analysis based on three randomized clinical trials', Depression and Anxiety, vol. 25, no. 7, pp. 565-574. https://doi.org/10.1002/da.20305

Short psychodynamic supportive psychotherapy, antidepressants, and their combination in the treatment of major depression: A mega-analysis based on three randomized clinical trials. / de Maat, S.C.M.; Dekker, J.J.M.; Schoevers, R.A. et al.
In: Depression and Anxiety, Vol. 25, No. 7, 2008, p. 565-574.

Research output: Contribution to Journal › Article › Academic › peer-review

TY - JOUR

T1 - Short psychodynamic supportive psychotherapy, antidepressants, and their combination in the treatment of major depression: A mega-analysis based on three randomized clinical trials

AU - de Maat, S.C.M.

AU - Dekker, J.J.M.

AU - Schoevers, R.A.

AU - van Aalst, G.

AU - Natijk, C.G.

AU - Hendriksen, M.

AU - Kool, S.

AU - Peen, J.

AU - Van, R.

AU - de Jonghe, F.

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AB - The efficacy of Short Psychodynamic Supportive Psychotherapy (SPSP) has not yet been compared with pharmacotherapy. A mega-analysis based on three original Randomized Clinical Trials (RCTs) was performed. Patients with (mild to moderate) major depressive disorder were randomized in (24 weeks) SPSP (n = 97), pharmacotherapy (n = 45), or their combination (n = 171). Efficacy was assessed by the Hamilton Depression Rating Scale (HDRS), Clinical Global Impression of Severity and of Improvement (CGI-S), the Symptom Checklist (SCL; depression subscale) and the Quality of Life Depression Scale (QLDS). Pearson χ

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DO - 10.1002/da.20305

M3 - Article

SN - 1091-4269

VL - 25

SP - 565

EP - 574

JO - Depression and Anxiety

JF - Depression and Anxiety

IS - 7

ER -

Short psychodynamic supportive psychotherapy, antidepressants, and their combination in the treatment of major depression: A mega-analysis based on three randomized clinical trials

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