TY - JOUR
T1 - Simultaneous determination of tyrosine, phenylalanine and deoxyguanosine oxidation products by liquid chromatography-tandem mass spectrometry as non-invasive biomarkers for oxidative damage
AU - Orhan, H.
AU - Vermeulen, N.P.E.
AU - Tump, C.
AU - Zappey, H.
AU - Meerman, J.H.N.
PY - 2004
Y1 - 2004
N2 - We developed an isotope dilution HPLC-atmospheric pressure chemical ionization-tandem mass spectrometry (HPLC-APCI-MS/MS) method for the simultaneous determination of p-tyrosine, phenylalanine, o,o′-dityrosine, m-tyrosine, o-tyrosine, 3-chlorotyrosine and 3-nitrotyrosine and 8-hydroxy-2′-deoxyguanosine (8-OHdG) that requires no extensive sample pre-treatment. p-[
AB - We developed an isotope dilution HPLC-atmospheric pressure chemical ionization-tandem mass spectrometry (HPLC-APCI-MS/MS) method for the simultaneous determination of p-tyrosine, phenylalanine, o,o′-dityrosine, m-tyrosine, o-tyrosine, 3-chlorotyrosine and 3-nitrotyrosine and 8-hydroxy-2′-deoxyguanosine (8-OHdG) that requires no extensive sample pre-treatment. p-[
U2 - 10.1016/j.jchromb.2003.10.056
DO - 10.1016/j.jchromb.2003.10.056
M3 - Article
VL - 799
SP - 245
EP - 254
JO - Journal of Chromatography B
JF - Journal of Chromatography B
SN - 1570-0232
IS - 2
ER -
