TY - JOUR
T1 - Skeletal muscle capillarization and oxidative metabolism in healthy smokers
AU - Wust, R.C.I.
AU - Jaspers, R.T.
AU - van der Laarse, W.J.
AU - Degens, H.
PY - 2008
Y1 - 2008
N2 - We investigated whether the lower fatigue resistance in smokers than in nonsmokers is caused by a compromised muscle oxidative metabolism. Using calibrated histochemistry, we found no differences in succinate dehydrogenase (SDH) activity, myoglobin concentration, or capillarization in sections of the vastus lateralis muscle between smokers and nonsmokers. The relationship between fatigue resistance and SDH activity in nonsmokers (r = 0.93; p = 0.02) is absent in smokers. This indicates that the lower muscle fatigue resistance of smokers can likely be attributed to causes other than differences in oxidative metabolism and capillarization. © 2008 NRC.
AB - We investigated whether the lower fatigue resistance in smokers than in nonsmokers is caused by a compromised muscle oxidative metabolism. Using calibrated histochemistry, we found no differences in succinate dehydrogenase (SDH) activity, myoglobin concentration, or capillarization in sections of the vastus lateralis muscle between smokers and nonsmokers. The relationship between fatigue resistance and SDH activity in nonsmokers (r = 0.93; p = 0.02) is absent in smokers. This indicates that the lower muscle fatigue resistance of smokers can likely be attributed to causes other than differences in oxidative metabolism and capillarization. © 2008 NRC.
U2 - 10.1139/H08-116
DO - 10.1139/H08-116
M3 - Article
SN - 1715-5312
VL - 33
SP - 1240
EP - 1245
JO - Applied Physiology, Nutrition, and Metabolism
JF - Applied Physiology, Nutrition, and Metabolism
IS - 6
ER -