Social dysfunction across neuropsychiatric disorders: Cognitive and neurobiological studies

Cross-disorder research is crucial to advance neuropsychiatric research. Social dysfunction, an early and common symptom, spans across major neuropsychiatric disorders. This thesis integrated data from multiple domains (i.e., (social) behaviour, cognition, neuroimaging) to provide evidence of several transdiagnostic cognitive and neurobiological factors associated with social dysfunction in neuropsychiatric disorders, with a particular role of the functional integrity within the default mode network. Future studies should incorporate these findings to improve personalised care initiatives rooted in social behaviour.