Abstract
Social dysfunction is a maladaptive process of coping, problem solving, and achieving one's goals. A new definition of apathy was cross-linked to social dysfunction, with a reduced goal-directed behavior and social interaction as a separate dimension. We hypothesized that these two neuropsychiatric symptoms may be included in the mild behavioral impairment diagnostic framework, operationalizing and standardizing late-life neuropsychiatric symptom assessment, to improve risk determination of dementia. Social dysfunction and apathy were transdiagnostic and prodromic for late-life cognitive disorders. A transdiagnostic approach could provide a useful mean for a better understanding of apathy and related conditions such as social behavior.
| Original language | English |
|---|---|
| Pages (from-to) | S57-S61 |
| Number of pages | 5 |
| Journal | Journal of Alzheimer's Disease |
| Volume | 100 |
| Issue number | s1 |
| Early online date | 12 Jul 2024 |
| DOIs | |
| Publication status | Published - 20 Aug 2024 |
Bibliographical note
Publisher Copyright:© 2024 - IOS Press. All rights reserved.
Funding
This paper was supported by the Project \"Development of an ensemble learning-based, multidimensional sensory impairment score to predict cognitive impairment in an elderly cohort of Southern Italy\" funded by the European Union - Next Generation EU - NRRP M6C2 - Investment 2.1 Enhancement and Strengthening of NHS biomedical research (Grant Agreement PNRRMAD- 2022-12376656).
| Funders | Funder number |
|---|---|
| European Commission | PNRRMAD- 2022-12376656 |
Keywords
- Alzheimer's disease
- apathy
- biopsychosocial frailty
- dementia
- depression
- late-life cognitive disorders
- mild behavioral impairment
- mild cognitive impairment
- social dysfunction
- social withdrawal