An efficient combination of MAO-N-catalyzed desymmetrization of cyclic meso-amines with Ugi-Smiles multicomponent chemistry produced optically pure N-aryl proline amides. This method represents the first report of a fully asymmetric Ugi-Smiles process.
- Amides/chemical synthesis
- Amines/chemical synthesis
- Models, Molecular
- Proline/chemical synthesis
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Znabet, A. (Contributor), Blanken, S. (Contributor), Janssen, E. (Contributor), De Kanter, F. J. J. (Contributor), Helliwell, M. (Contributor), Turner, N. J. (Contributor), Ruijter, E. (Contributor) & Orru, R. (Contributor), Unknown Publisher, 1 Jan 2012