Stress exposure across the life span cumulatively increases depression risk and is moderated by neuroticism

C.H. Vinkers, M. Joels, Y. Milaneschi, R. S. Kahn, B.W.J.H. Penninx, M.P.M. Boks

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Background: Even though traumatic stress is a major risk factor for depression, most people do not develop a depression. The effects of stress may particularly emerge after repeated exposure in vulnerable individuals. Therefore, we hypothesized that (1) increased exposure to stress across the life span is associated with an increased depression risk and (2) this effect is the most pronounced in individuals with high levels of neuroticism.
    Original languageEnglish
    Pages (from-to)737-745
    JournalDepression and Anxiety
    Volume31
    Issue number9
    DOIs
    Publication statusPublished - 2014

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